Protein
MCA_00590_1
Length
572 amino acids
Gene name: ALG8
Description: Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Browser: contigA:1815656-1817375-
RNA-seq: read pairs 2429, FPKM 52.4, percentile rank 66.4% (100% = highest expression)
Protein function
| Annotation: | ALG8 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase | |
|---|---|---|---|
| KEGG: | K03849 | ALG8 | alpha-1,3-glucosyltransferase [EC:2.4.1.265] |
| EGGNOG: | 0PIKP | ALG8 | Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol |
| SGD closest match: | S000005593 | ALG8 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase |
| CGD closest match: | CAL0000180957 | ALG8 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00943_1 | 77.38% | 557 | 0.0 | MIA_00943_1 |
| A0A0J9XH24_GEOCN | 69.23% | 533 | 0.0 | Alpha-1,3-glucosyltransferase OS=Geotrichum candidum GN=BN980_GECA16s00725g PE=3 SV=1 |
| A0A060T0W9_BLAAD | 64.33% | 541 | 0.0 | Alpha-1,3-glucosyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11770g PE=3 SV=1 |
| A0A1E3PNH3_9ASCO | 60.04% | 538 | 0.0 | Alpha-1,3-glucosyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45943 PE=3 SV=1 |
| UniRef50_A0A1E3QTV4 | 53.87% | 568 | 0.0 | Glycosyltransferase family 57 protein n=1 Tax=Babjeviella inositovora NRRL Y-12698 TaxID=984486 RepID=A0A1E3QTV4_9ASCO |
| Q6CGP5_YARLI | 52.36% | 573 | 0.0 | Alpha-1,3-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A17512g PE=3 SV=1 |
| ALG8_CANAL | 50.52% | 572 | 0.0 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ALG8 PE=3 SV=2 |
| ALG8_YEAST | 47.92% | 576 | 1e-174 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALG8 PE=1 SV=1 |
| A0A1E4TH49_9ASCO | 43.31% | 538 | 4e-130 | Alpha-1,3-glucosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2728 PE=3 SV=1 |
| A0A167F5U5_9ASCO | 26.90% | 435 | 4e-31 | Alpha-1,3-glucosyltransferase OS=Sugiyamaella lignohabitans GN=ALG6 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9791
Predicted cleavage: 48
Protein family membership
- Glycosyl transferase, ALG6/ALG8 (IPR004856)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF03155 (Alg6_Alg8)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_00590_1 MKRRSNTPSAKGLKSALKSSPKLTKLPSNTPHAATNQRPLSLKNIFIAATFLKVLLFVAYHSTDFDVHRNWLAITANLPL RQWYTEATSQWTLDYPPFFAYFEYILTWFVPQVVKDDGCLDIVEKGNYGWPTIAFQRTTVIVTEILLFCALQYYIDTRGE NHDETVSAVADETVRDSAKRYKKLQAFAVAGSIALSPGLLIIDHIHFQYNGFMYGILIFSLVAAMNNRPLLSGALFAILL CFKHIYLYLAPAYFVYLLRVYCLDSPKPSKTASNKSSVLGIPAIWPIKGINWSHVTKLGAAVVTPFVLAFGPFVYYNQMP AVLSRLFPFSRGLTHAYWAPNVWAVYSFVDRVLGFVYGKSSAGSTRGLVGDVTFSVLPDITPRLTFLLTLFYMVLALIPL FLWPTVSRFLASVTLCGYASFLFGWHVHEKAVLLIIFPFSFLALKDSRLLSTFVPLTVSGYISLFPLIFTSGESILKTSY TFVWFVMFHLSFENLVQVRKVQRHVFLLDRARLLYMIGFVPLMIMGFATEHFLPARFEFASLMAISVYCSIGVIGSWAGF TWLYFFDEEIWN
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0016758 transferase activity, transferring hexosyl groups
Cellular Component
GO:0005789 endoplasmic reticulum membrane