MCA_00579_1

Protein

Length

359 amino acids

Description: Putative palmitoyl-protein thioesterase

RNA-seq: read pairs 461, FPKM 15.8, percentile rank 35.2% (100% = highest expression)

Protein function

Annotation:			Putative palmitoyl-protein thioesterase
KEGG:	K01074	PPT	palmitoyl-protein thioesterase [EC:3.1.2.22]
EGGNOG:	0PMHB	FG04980.1	Palmitoyl-protein thioesterase
CGD closest match:	CAL0000191043	CAALFM_CR04490CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_03571_1	55.02%	289	1e-116	MIA_03571_1
A0A0J9XDB7_GEOCN	53.61%	263	7e-111	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA10s02111g PE=4 SV=1
UniRef50_A0A0J9XDB7	53.61%	263	1e-107	Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDB7_GEOCN
Q6C1R3_YARLI	52.57%	272	4e-102	YALI0F14135p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F14135g PE=4 SV=1
A0A060TI83_BLAAD	49.64%	274	2e-98	ARAD1D36872p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36872g PE=4 SV=1
Q5A6L4_CANAL	47.39%	268	5e-88	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR04490CA PE=4 SV=1
A0A1E3PN33_9ASCO	43.30%	291	6e-79	Alpha/beta-hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50519 PE=4 SV=1
A0A1E4TJE5_9ASCO	43.28%	268	7e-78	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19081 PE=4 SV=1
A0A167CAN0_9ASCO	32.12%	137	1e-17	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_4245 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3844

Protein family membership

Palmitoyl protein thioesterase (IPR002472)

Domains and repeats

Domain
79 - 354
Alpha/Beta hydrolase fold (IPR029058)

1 50 100 150 200 250 300 359

Detailed signature matches

IPR002472

Palmitoyl protein thioesterase
1. PR00414 (PPTHIESTRASE)
  
  330 - 348
  
  PRINTS
  PR00414 (PPTHIESTRASE)
  
  76 - 98
  
  PRINTS
  PR00414 (PPTHIESTRASE)
  
  286 - 304
  
  PRINTS
  PR00414 (PPTHIESTRASE)
  
  155 - 171
  
  PRINTS
  PR00414 (PPTHIESTRASE)
  
  115 - 134
  
  PRINTS
  PR00414 (PPTHIESTRASE)
  
  233 - 252
  
  PRINTS
  PR00414 (PPTHIESTRASE)
2. PF02089 (Palm_thioest)
  
  80 - 343
  
  Pfam
  PF02089 (Palm_thioest)
IPR029058

Alpha/Beta hydrolase fold
1. SSF53474 (alpha/bet...)
  
  79 - 352
  
  SUPERFAMILY
  SSF53474 (alpha/beta-Hydrolases)
2. G3DSA:3.40.50...
  
  79 - 354
  
  GENE3D
  G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

21 - 359

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 20

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

16 - 20

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

4 - 15

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 3

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
SignalP-noTM

1 - 20

SignalP euk
SignalP-noTM (SignalP-noTM)
TMhelix

7 - 29

TMHMM
TMhelix (TMhelix)

Protein sequence

>MCA_00579_1
MNILSLLVLHILLLVSPISCAYIGITQIHPESILNRQFLSGSNNFGLQKILSNLSPFKKQPQADTHSLKHDEDVLTPTLP
PPRPVVIWHGLGDTYDSTGMKRAAAAIKNAKPHTFVYAIRLSNDSSSDQQATLFGKVNEQIDIVCNDLKRIPELQNGFDA
IGFSQGGVFLRGYIERCNNPPVGSLMTFGSPHNGIAALPLCGKTDFLCRNRNRLFEANVYTDYSQEHIVSAQYYRDPNRY
EEYLEKSRYLADVNNERAEKNKTYSENLGSIEKFIMVMFDQDVTVVPKESAWFQEYNKTTHVLTPLEQRDLYLKDWIGLK
RLGDKNGIVYVSLPGQHMQISSSDLKTLVSEYFVTNSTL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0098599 palmitoyl hydrolase activity

Cellular Component