Protein

MCA_00571_1

Length
1,228 amino acids


Gene name: SMP3

Description: GPI mannosyltransferase 4

Browser: contigA:1762132-1765819+

RNA-seq: read pairs 1434, FPKM 14.4, percentile rank 33.2% (100% = highest expression)

Protein function

Annotation:SMP3GPI mannosyltransferase 4
KEGG:K08098PIGZ phosphatidylinositol glycan, class Z [EC:2.4.1.-]
EGGNOG:0PG7ISMP3Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi
SGD closest match:S000005675SMP3GPI mannosyltransferase 4
CGD closest match:CAL0000175734SMP3GPI mannosyltransferase 4

Protein alignments

%idAln lengthE-value
MIA_02852_157.43%4518e-148MIA_02852_1
A0A0J9XK77_GEOCN52.51%4385e-152Mannosyltransferase OS=Geotrichum candidum GN=BN980_GECA32s01451g PE=3 SV=1
UniRef50_A0A0J9XK7752.51%4381e-148Mannosyltransferase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XK77_GEOCN
A0A161HJK3_9ASCO43.86%5292e-129Mannosyltransferase OS=Sugiyamaella lignohabitans GN=SMP3 PE=3 SV=1
A0A060SY73_BLAAD47.95%4385e-128Mannosyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A14190g PE=3 SV=1
A0A1E3PH47_9ASCO48.62%4361e-127Mannosyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83640 PE=3 SV=1
SMP3_YARLI40.83%4098e-86GPI mannosyltransferase 4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SMP3 PE=3 SV=1
SMP3_CANAL34.61%4192e-71GPI mannosyltransferase 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SMP3 PE=3 SV=2
A0A1E4TKF7_9ASCO51.16%1293e-29Mannosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42856 PE=3 SV=1
SMP3_YEAST34.86%2182e-27GPI mannosyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMP3 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1051

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF03901 (Glyco_tran...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00571_1
MTSRVDQNPNQQKQLKDSPLPTSISASSTRSASSIQRSTVSSAYSNVSSMHISSSLASKKRGHNQIPAASRSQLPHVANP
GLSNKGNIHSSQHPLPPGGSTPPHHNNTFLSNRLFENSHSNKFLTASISKSSKHNSHLVRTTSGRIISKSRSSSALKNQI
TLDTHHQSMHNGIFNTVTDDDESIDTHSSKSVSHSPAPPSTNNPPQPRISFPEVARPKLSSAPTTTQATRSPSPLEDIPT
FSSSYLNSNMMDFGNESPLYFDGNSIYSVSESNNMPSNLISNHSQHSPTDSEKNNANNKFEPNENFNDETHSHDDPQILA
QKMRGSISSTSPSNSYTSVALESSSSSISSTCSNSTVKSRSQSRSRSKQSTSPSRNSLDSQTLTQKRKASHDGSYENKAT
PVFSSSWHWKTIFIISIILRTYFSLSPSYIHPDEHFQGPEAIADMIFGWATKKSWEFSSASPARSYFVAWVVYGIPMFFL
KLIYAPSPTSINPQAVLHGLRLTFALGNWVLSDMAIDRLTQSKDHKLSSLFFYATSYVTWTYQSHTFSNSVETVILLWCL
VIIYEFQTKTKKRQIASPARFWDGFLLGILVAFGIFNRITFPAFLFIPAIRSLPIFFKYPGTLFMAALGFSITCILAIYF
DSVCFSFLDPNSPSYAQYPFFVTNTISSSSSSSIFSLFKLASTTNFFKQHTITTSSKLVITPLNNLFYNLQTDNLALHGI
HSRLHHFLVNIPELMGPGILLLLSTRFIKSLPFQSAISGIFILSLVQHQEARFLLPAIPLLCCSLDVSIVPKKFRGIFFT
IWIAFNVIMGVLMGILHQGGVIPAQGYLSQLTVSPFASTLSKFSGSLHLSNMSPYQRERDFGVQCASPVDFIDKLSNSEE
TSPAFASINGNDGLVYNNFGGSINTPKYVYYDYNRDGNPAGNLKEEKQCNAGTQAKNDIANSTGSPEVVTDYVILWWKTY
SPPIWMLGKDLDDVDIIDPIESIPGGGENWARYQTIFSFLDALKSSVVGMNVNKENEKSSTFSETDERNKETLSKLDQST
KLDPAMPSGETEDSSVKQELIKFHSRHKYYSAIHPHITVVDMMGANRPLLKTVLKKLANISKTAQSNITNNNINGGINQR
IYPRRVIKTYLVAPIATILTSLDSEKAEINCIETIFKTSVSDATGNVPVTGKDNNNTTSIETLGLLDNDLYKFKKVWTTK
SHLSLDDLDFTNWKSLVPGLAIYEMEIK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016757 transferase activity, transferring glycosyl groups

Cellular Component

None predicted.