Protein

MCA_00547_1

Length
2,060 amino acids


Gene name: BST1B

Description: GPI inositol-deacylase

Browser: contigA:1703365-1709630-

RNA-seq: read pairs 523, FPKM 3.1, percentile rank 13.9% (100% = highest expression)

Protein function

Annotation:BST1BGPI inositol-deacylase
EGGNOG:0PGPBBST1Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins (By similarity)
SGD closest match:S000001869BST1GPI inositol-deacylase
CGD closest match:CAL0000175277BST1GPI inositol-deacylase

Protein alignments

%idAln lengthE-value
MIA_03089_151.46%10240.0MIA_03089_1
A0A0J9X2Z1_GEOCN42.11%10070.0Similar to Saccharomyces cerevisiae YFL025C BST1 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation OS=Geotrichum candidum GN=BN980_GECA01s07259g PE=4 SV=1
UniRef50_A0A0J9X2Z142.11%10070.0Similar to Saccharomyces cerevisiae YFL025C BST1 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2Z1_GEOCN
A0A161HJ80_9ASCO38.22%10027e-171Bst1p OS=Sugiyamaella lignohabitans GN=BST1 PE=4 SV=1
A0A1E3PS57_9ASCO35.03%9853e-147PGAP1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82079 PE=4 SV=1
A0A1E4TAG8_9ASCO47.33%3742e-95Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11696 PE=4 SV=1
BST1_YEAST42.78%3532e-75GPI inositol-deacylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BST1 PE=1 SV=1
A0A060TBN4_BLAAD43.34%3532e-69ARAD1B17028p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B17028g PE=4 SV=1
BST1B_YARLI37.89%3511e-63GPI inositol-deacylase B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BST1B PE=3 SV=1
BST1_CANAL32.87%3593e-37GPI inositol-deacylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BST1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0581

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 2060

Detailed signature matches

    1. PF07819 (PGAP1)
    1. SSF53474 (alpha/bet...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00547_1
MNVLFPRWRYTISDSNPEISDDTTINNNNININNNQQLHSAFINESVSGSLSSSIFSNTNHTQSSPNGFYHCPSPVSSTT
LLSQIPPASPKQAIIAACTADSQNLKSSAESLPITATNVPSQTFSVPTVHTGNKSRRKKLSDDNVSPEPQPPHLQSLNPS
PSPSLTSCSSYTPTDHSLEDFENTDSSTENFNEFENSFLRKRCPSIHPHSFPLDSPQIMHHWNSLNQYNSSLAHTGASAS
LSTSSTITHSTVEGFNLPFDDTCRRHQSSQPNHIKPLINDVDNCENSKLNANKIDSTNCNITKNVLEQNKAKFQSTTSCD
LAVPARTTNVASSPHTEHTLEFKDTLFTRSFDPISASQSSNLPHVPQQQSFRKNLHLNTSFNKSNITSSDINPNAQKSYY
FSPGPNEEMIQNLSETFPTHYAPANGIRKSLFKLFSKVSCLSLSVLCVLTIALMLISSVSFNYKEHQDAASCRMSYMSPS
YVLLDSFNQNYTRHHSKYSLYLYREKGIDDAFPNPTGIPVLFIPGNAGSFRQVRALAAKSATLFFSNPYKHPQFDYYTAD
FNEDLTAFHGRSLLDQAEYLNDAIKFILSLYSPIKNNTISNNEESIESTNDAEESFDENLENDENAQKLYPSPKSVILIG
HSMGGVVARTMLMLENYNKGSVNTIFTLSAPHTLPPAPFDKELVSIYDSVNDFWERSFSQDFIGRNPLDQVSLVSITGGP
IDTMITSESTSISSIVPPSNGFTVYTSSIPYVWGGIDHQAIVWCDQFRDVFAATLSEISDPRSSTKTKSLISRMKSFRSH
FLGGFQSEASSEYLQTKYHPTLGGNTPPDSINNVNTKQKPISVFVPSSVGTHDTLLWVNDITKFNTPPGKQLIIRNLGRK
NNENNFQDSSGRVYFMPISSDLISVPKNDLEFTLLTDQKLISYEDSMNKQKSTTFSSPDSEDFFHGSPDLETDKTTETVV
PYNFKSGRVNHGLYAMACKYPHAEVRLSGTSLNVIDLTKGGFKDGTSEMNADISSHNAKSKAESKNGFEPINEEDDPKLV
GLLCKNIAGDASILPNPYGKEKVHLSLKNERESHVIEQSEISGLSFIKYDATQLSDYDFITIIDTNPDPRPGFAIAEFST
KSGSRFNIDTNGRQLFPHVVSITLPPNRPFMVDISFEDIWSSLISYKITVIEHNLKHNGRSNQRRIQKIGENSEQLFQPF
IRQYAGDSYESKYHFDLLPDKDFSTNTSNLLKHIPINFSAVAPFSPFAIRELDTDFEANLFYMGQKSHHYHNLHLQLWSD
SSSNFISSSSSDYNTTLNTLEIQLKVDWLGSLGNLVMHYRIAVIAFPIAIISMVMFIQFRIYNNKGIFISCWDALKIFTS
KYLVYFMLLSTVLPYCNLPIFRDLIYILEPGMDVYSGDGPASIFTNIRRNQFFLGLEPGHLLFLGPLFMVMATGLATTVY
LLLYSIISMLSCIQWLFITYTSRIPFSTFRNENSLNLNQLENTNTPTALESIDKTSDASCSSYLLSPSPVSSPHFDTLSS
IPRRRNSPTLNAIQSPSSKVSQSFSSSSTVNDNNKTLVLFPWGSARIQTIRKIVVTIFLFVAVAYTIPCEFAYLVACFVQ
LSTVIRAHYRIYYFDKYYYSKQQRTNKRNISQQSSHSNIEGSISPSSEWFINGNGEKVSLNCFFNFAMSTLLLMLFIVPV
TAPILVVWGRKLTAHWNEAFQSHHNLLSIGPILFLVEIIASGKMIPRACSSGTSPVSKLGLNGSSLLNKTINTSETISDE
ASDNDLVLSIEDDKFPILDSTNLSSVLALGNETANVNSERLIDESITLITDTEESIKTASTGNATSDTATLNNNVLPKPE
IPNHYDDEIIQGNTENNCKFQKLVTYCSLWFITFNAIVLGIPRTYVLYHLVNILSGWFLLQFFIYPSTNVNIDIHPNDET
CDSADACSSFSHISSYKDGKLPPRNISENVKKMSKHSSTIIKKTKGFKRRRNTEVPVFQQMETYGSTHTIPRPLIQGVEY
SIDTPGRPASSVQPLRTRSNILTKIGGIENVAFRTPNDLNDEDFSLPDGYYQGYYDDNES

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016788 hydrolase activity, acting on ester bonds

Cellular Component

None predicted.