Protein

MCA_00538_1

Length
270 amino acids


Description: Putative NADP(+)-dependent serine dehydrogenase and carbonyl reductase, similar to YMR226C of S. cerevisiae

Browser: contigA:1679803-1680616+

RNA-seq: read pairs 2796, FPKM 127.5, percentile rank 82.7% (100% = highest expression)

Protein function

Annotation:Putative NADP(+)-dependent serine dehydrogenase and carbonyl reductase, similar to YMR226C of S. cerevisiae
KEGG:K16066ydfG 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]
EGGNOG:0QED2FG04260.1Dehydrogenase
SGD closest match:S000004839YMR226CNADP-dependent 3-hydroxy acid dehydrogenase
CGD closest match:CAL0000178772orf19.4633Oxidoreductase

Protein alignments

%idAln lengthE-value
MIA_02611_178.36%2684e-148MIA_02611_1
A0A060TJV8_BLAAD71.05%2667e-133ARAD1D49874p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D49874g PE=3 SV=1
A0A0J9XFY0_GEOCN73.03%2672e-130Similar to Saccharomyces cerevisiae YMR226C NADP(+)-dependent dehydrogenase OS=Geotrichum candidum GN=BN980_GECA14s01033g PE=3 SV=1
Q6CCQ8_YARLI67.67%2664e-124YALI0C07414p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07414g PE=3 SV=1
UniRef50_Q6CCQ867.67%2661e-120YALI0C07414p n=162 Tax=saccharomyceta TaxID=716545 RepID=Q6CCQ8_YARLI
A0A1E3PMI4_9ASCO60.97%2697e-112NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82414 PE=3 SV=1
A0A1E4TJR7_9ASCO62.69%2682e-110Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30293 PE=3 SV=1
YM71_YEAST52.45%2653e-96NADP-dependent 3-hydroxy acid dehydrogenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YMR226C PE=1 SV=1
Q5AML3_CANAL54.68%2671e-92Oxidoreductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4633 PE=4 SV=1
A0A167EYZ1_9ASCO70.59%1022e-49Oxidoreductase OS=Sugiyamaella lignohabitans GN=AWJ20_2229 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8237
Predicted cleavage: 13

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 270

Detailed signature matches

    1. PR00080 (SDRFAMILY)
    2. PR00081 (GDHRDH)
    3. PF00106 (adh_short)
    1. SSF51735 (NAD(P)-bi...)
    1. PS00061 (ADH_SHORT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PIRSF000126 (11-bet...)

Protein sequence

>MCA_00538_1
MATYGSKAAERLAGKTIFITGASAGIGKATTLELAAAANGNVKFILSARRVDKLKALKDELEDKYDAIKVLALEFDVSKY
NTIPDIVASLPEPFANVDVLINNAGMVHGVEKVGEINQADIEQMFNTNVLGMIALTQAFMPLFKKRGTGDIVNLGSIAGR
DPYPGGAIYCATKAALRSFSHSLRKEVIDTHIRVIEVDPGAVETEFSIVRYRGDKSKADAVYKGYEPMVAEDIAEIITFA
LTRRPNTVIAETLVFPTSQASASHVYRKPE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.