Protein

MCA_00537_1

Length
385 amino acids

Gene name: RIM11

Description: Serine/threonine-protein kinase RIM11/MSD1, in S. cerevisiae required for signal transduction during entry into meiosis

Browser: contigA:1675119-1676411-

RNA-seq: read pairs 3668, FPKM 117.4, percentile rank 81.4% (100% = highest expression)

Protein function

Annotation:RIM11Serine/threonine-protein kinase RIM11/MSD1, in S. cerevisiae required for signal transduction during entry into meiosis
KEGG:K03083GSK3B glycogen synthase kinase 3 beta [EC:2.7.11.26]
EGGNOG:0PGBMRIM11protein kinase gsk3
SGD closest match:S000004747RIM11Serine/threonine-protein kinase RIM11/MSD1
CGD closest match:CAL0000186692RIM11Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_02614_189.64%3860.0MIA_02614_1
A0A060T4L0_BLAAD82.12%3860.0ARAD1B04290p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B04290g PE=3 SV=1
A0A167DPB0_9ASCO80.88%3870.0Serine/threonine protein kinase RIM11 OS=Sugiyamaella lignohabitans GN=RIM11 PE=3 SV=1
UniRef50_W6R70877.52%3870.0Protein kinase gsk3 n=67 Tax=Eukaryota TaxID=2759 RepID=W6R708_PENRF
A0A1E3PHS7_9ASCO78.24%3860.0Glycogen synthase kinase-like protein-3 beta OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83096 PE=3 SV=1
Q6C8B8_YARLI78.24%3860.0YALI0D20966p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20966g PE=3 SV=2
A0A0J9XDY0_GEOCN80.32%3710.0Similar to Saccharomyces cerevisiae YMR139W RIM11 Protein kinase required for signal transduction during entry into meiosis OS=Geotrichum candidum GN=BN980_GECA11s03046g PE=3 SV=1
A0A1E4TCY5_9ASCO70.62%3880.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_141501 PE=3 SV=1
A0A1D8PH74_CANAL61.29%4032e-179Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIM11 PE=4 SV=1
RIM11_YEAST61.86%2914e-136Serine/threonine-protein kinase RIM11/MSD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIM11 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2031

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 385

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd14137 (STKc_GSK3)

Residue annotation

  1. ATP binding site c...
  2. active site cd14137
  3. dimer interface cd...
  4. polypeptide substr...
  5. activation loop (A...
  6. axin binding site ...

Protein sequence

>MCA_00537_1
MSQLVTKKVQDGKTGELKELVYTQQNVVGSGSFGIVFQTKLSPSGEDAAIKRVLQDKRFKNRELEIMRKVSHPNIVDLKA
FFYSNEKDEVYLNLVLEYIPETVYRALRYFSKQKTSMPMIEVKLYTYQLFRSLAYIHALGICHRDIKPQNLLLNPKTGVL
KLCDFGSAKILVQGEPNVSYICSRYYRAPELIFGATNYTTKIDVWSSGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTP
TREQIRTMNPNYVEHKFPQIKPHPFAKVFKKATPDAIDLISRLLEYSPGVRLSAIEAMAHPFFDELRDPNTRLPDSRNIS
ANGHSGPSLRDLPPLFNFTELELSIAPELNSRLVPPHARPQLAARGIDLDRFVPLRPDQIRTTLN

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.