Protein

MCA_00508_1

Length
704 amino acids


Gene name: DUR3A

Description: Urea active transporter

Browser: contigA:1599765-1601880-

RNA-seq: read pairs 58, FPKM 1.0, percentile rank 9.3% (100% = highest expression)

Protein function

Annotation:DUR3AUrea active transporter
KEGG:K20989DUR3 urea-proton symporter
EGGNOG:0PH3RPGUG_02455Urea active transporter
SGD closest match:S000001008DUR3Urea active transporter
CGD closest match:CAL0000194064DUR3Dur3p

Protein alignments

%idAln lengthE-value
MIA_00786_168.83%6930.0MIA_00786_1
A0A0J9XJM6_GEOCN62.93%6960.0Similar to Saccharomyces cerevisiae YHL016C DUR3 Plasma membrane transporter for both urea and polyamines OS=Geotrichum candidum GN=BN980_GECA23s00087g PE=3 SV=1
Q6CFS8_YARLI58.02%7360.0YALI0B04202p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B04202g PE=3 SV=1
UniRef50_Q6CFS858.02%7360.0YALI0B04202p n=46 Tax=Ascomycota TaxID=4890 RepID=Q6CFS8_YARLI
A0A1E4T9M7_9ASCO59.26%6530.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_146491 PE=3 SV=1
DUR3_YEAST51.91%7070.0Urea active transporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DUR3 PE=1 SV=2
A0A1D8PDB5_CANAL53.04%7240.0Dur3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DUR3 PE=3 SV=1
A0A161HL45_9ASCO60.63%5740.0Dur3p OS=Sugiyamaella lignohabitans GN=DUR3 PE=3 SV=1
A0A060T9S5_BLAAD53.16%6810.0ARAD1D16852p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D16852g PE=3 SV=1
A0A1E3PGG2_9ASCO65.22%2071e-72Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70957 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1652

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF00474 (SSF)
    2. PS50283 (NA_SOLUT_S...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. cd11476 (SLC5sbd_DUR3)
  3. mobidb-lite (disord...)

Residue annotation

  1. Na binding site cd...

Protein sequence

>MCA_00508_1
MAEAPLPQGAGYAVVVGLGFAFSFFLMFMTYILRRYQQKAVSSEEFNTAGRSVGKGLIASAVVSSWTWAATLLQSTAQAY
KNGVSGPFWYASGATVQVILFATIAVELKKKAPGAHTYLEVIKVRYGAIGHCVFLFFALCTNILVTSMLLTGGTAVISFL
TGMHVIAATLLLPLSVAMFTFFGGIKATFLSDYIHTIMLITIILVFTFTAYCTSSLEGVGSFGAIWEKLTERGITDPIEG
NAGGSYLTMRSRSGGIFFVINIIGNFGTVFLDNGYWNKAISAAPQSAYPGYLLGAAAWFVIPWLCATTMGLSALALEDTP
AFPTYPNPMTPQEVSAGLVLPNAAVALLGKGGAVAALLLVFMAVISTFSAELIAASSIGTYDIYKSYINPKASGKSLVYI
SHGCVLAFAFGIAGFSIALYYIGISMGYLYLLMGIIISAAVIPVTLALFWKGQNFYAAVCSPVLGFISALVAWLVTAKAK
FGELTVETTNADMPMLAGNVVALLSPLVFITIFTLIFKPDNFDFEELKKIRKDKEDVTLTETDPEANETIIVEEEQDNNN
EFEYQSPEEIAILRKYSLWARVIVVILALCLLVIWPMPMYGSGYIFSKQFFTGWVIVGIIWIFVSLFIVGFIPLWDGRQQ
IYFTLRGLYWDVTGQSHKLRKWQQDHKASLENQEKSVIHITGKQGENDGTETPNEITTKLSEKS

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016020 membrane