Protein

MCA_00494_1

Length
425 amino acids


Gene name: RPT5

Description: 26S proteasome regulatory subunit 6A

Browser: contigA:1562757-1564106+

RNA-seq: read pairs 6035, FPKM 175.0, percentile rank 86.5% (100% = highest expression)

Protein function

Annotation:RPT526S proteasome regulatory subunit 6A
KEGG:K03065PSMC3 26S proteasome regulatory subunit T5
EGGNOG:0PFP3RPT526S protease regulatory subunit 6A
SGD closest match:S000005643RPT526S proteasome regulatory subunit 6A
CGD closest match:CAL0000178035RPT5Proteasome regulatory particle base subunit

Protein alignments

%idAln lengthE-value
MIA_04878_189.60%4230.0MIA_04878_1
A0A0J9XK12_GEOCN90.12%4050.0Similar to Saccharomyces cerevisiae YOR117W RPT5 One of six ATPases of the 19S regulatory particle of the 26S proteasome OS=Geotrichum candidum GN=BN980_GECA27s00747g PE=3 SV=1
A0A060T6K0_BLAAD88.40%4050.0ARAD1C14652p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14652g PE=3 SV=1
A0A167D905_9ASCO87.90%4050.0Proteasome regulatory particle base subunit RPT5 OS=Sugiyamaella lignohabitans GN=RPT5 PE=3 SV=1
A0A1E3PJH4_9ASCO88.15%4050.026S proteasome subunit P45 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83168 PE=3 SV=1
Q6C9Q7_YARLI86.07%4020.0YALI0D09119p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D09119g PE=3 SV=1
UniRef50_A0A099P7J984.28%4070.0Uncharacterized protein n=66 Tax=Eukaryota TaxID=2759 RepID=A0A099P7J9_PICKU
A0A1D8PMQ4_CANAL82.84%4080.0Proteasome regulatory particle base subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPT5 PE=3 SV=1
PRS6A_YEAST78.88%4120.026S proteasome regulatory subunit 6A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPT5 PE=1 SV=3
A0A1E4TLG1_9ASCO83.29%4070.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_89290 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1025

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 425

Detailed signature matches

    1. SSF52540 (P-loop co...)
    1. SM00382 (AAA_5)
    1. PF00004 (AAA)
    1. PS00674 (AAA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00009 (AAA)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_00494_1
MADLDEQMKDVVEDEIDEEILNASTSDIITRRHLLANDIKVMKSEDHRLTHEKTVLEEKIRDNREKIENSKQLPYLVGNV
VELLDMEAEKTEEGSNVDLDSTHVGKSAVIKTSTRQTVFLPLIGLVDPENLKPGDLIGVNKDSYLILDTLPAEYDSRVKA
MEVDEKPTETYQDIGGLAKQIEELDEAVVSPMKQADKFKKLGIKAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAP
QLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSDKSGDREVQRTMLELLNQLDGFGSDDRVKVLAATNR
VDVLDPALLRSGRLDRKIEFPLPTEEARANILQIHSKKMTVDDSINWEELARSTDEFNGAQLKAVCVEAGMIALRLGKSK
ISHEDYVEAITEVQARKSKSVSFYA

GO term prediction

Biological Process

GO:0030163 protein catabolic process

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

GO:0005737 cytoplasm