Protein

MCA_00491_1

Length
909 amino acids


Description: protein with Zn(2)C6 fungal-type DNA-binding domain

Browser: contigA:1551510-1554240-

RNA-seq: read pairs 2403, FPKM 32.6, percentile rank 55.1% (100% = highest expression)

Protein function

Annotation:protein with Zn(2)C6 fungal-type DNA-binding domain
EGGNOG:0PMSGPGUG_02878transcriptional activator protein
SGD closest match:S000002329UGA3Transcriptional activator protein UGA3
CGD closest match:CAL0000178565UGA3Uga3p

Protein alignments

%idAln lengthE-value
MIA_05911_178.77%2121e-113MIA_05911_1
A0A0J9X3G4_GEOCN61.99%2217e-85Similar to Saccharomyces cerevisiae YDL170W UGA3 Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (Such as UGA1,UGA2, UGA4) OS=Geotrichum candidum GN=BN980_GECA02s04036g PE=4 SV=1
UniRef50_A0A0J9X3G461.99%2211e-81Similar to Saccharomyces cerevisiae YDL170W UGA3 Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (Such as UGA1,UGA2, UGA4) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3G4_GEOCN
A0A060T5G0_BLAAD48.80%2096e-60ARAD1B10978p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10978g PE=4 SV=1
A0A161HHF9_9ASCO44.33%2033e-53Uga3p OS=Sugiyamaella lignohabitans GN=UGA3 PE=4 SV=1
A0A1E3PIW6_9ASCO50.58%1727e-45Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_66016 PE=4 SV=1
Q6C8E2_YARLI37.17%1914e-40YALI0D20394p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20394g PE=4 SV=1
A0A1D8PU36_CANAL40.65%1553e-32Uga3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UGA3 PE=4 SV=1
UGA3_YEAST27.69%2421e-21Transcriptional activator protein UGA3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UGA3 PE=1 SV=1
A0A1E4TIG3_9ASCO56.10%411e-11Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_72 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6428
Predicted cleavage: 43

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 909

Detailed signature matches

    1. PF11951 (Fungal_tra...)
    1. PF00172 (Zn_clus)
    2. PS00463 (ZN2_CY6_FU...)
    3. SM00066 (gal4_2)
    4. SSF57701 (Zn2/Cys6 ...)
    5. PS50048 (ZN2_CY6_FU...)
    6. cd00067 (GAL4)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Residue annotation

  1. DNA binding site c...
  2. Zn2+ binding site ...

Protein sequence

>MCA_00491_1
MLNAQASLSSNTPALSHNSLSSKSSSPPSYSYNNADLKQPRQRSRNGCFTCRKRKKRCDEGKPVCNACTRLSLECTYPIP
GQERKNKKRKSQLADEHKSNSGNSQQSSTSADEGPSPSKRSKHSSNKPSKPRVAENNKSRSSSQPSLSTSSQNDMPSLPS
SKYDSPSETSSINYTQLLKDNHPRYAALVGLSSPLPTTFGADLSHSEFDAIESLVKTTSGIFSSAGTPHNNTETHNNSNN
ISSSNNNTFSPGTFNSMMNGFQSPFFGPLTPQQAQQQGSSDFLNPTLGENLSTDPANASNAAGSASPSSHANSNSGGRRS
SYHSPQFRFSSAEIFSPNVAMAAAAAAAAAAVSNSPNLFPRSIHSLIASPTFPPSSPRIELLDSQGNPEVTENNQDKSAD
TEDTLNRQFQNSHDVISSFNQELDFPYLDNDDLDNEKDKYDGQYSPLALCSSPSPWYASYLDNIGIEMFAYYNNYLANMI
NVSSKINSFLNVFVPMAQEDPSVLYALVAYASFHHSMGRHEDVGLRYLNTAIKMARNDLPKHKLTTLAAILIISTAEICK
GDMVHWNRHLNAAADVIQMRGGMEHFVNDPTKRWLATNFVYHDILAASKYEHKPHFEPKDYNMILRMDPGVHSLIGCCKP
IFALMAEISDLAVEAQEIYSQYSSSKRSKKNKEENKSSSSPEQASSSPSSLSSSSTNEGSPASRIMNMKIDSNYHNFNKD
ENNDDDDDENESVDSFLMPSVQRKLIDKMKDLHDRARELEQRIDTCKPDPNDIMNLKSGDLEEQLTLFETFQLAAKLHLL
QSVFRRNAGCLEMQVIACELTTSLDVVLNTKVEASVVFPLFIAGIMATSDRQRQAMMARFDGFYKRQLARNIVRACNLAE
EVWKLDHHGTKYVNWYKVIQQHGWDICFS

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus