Protein

MCA_00484_1

Length
662 amino acids

Gene name: PPZ1B

Description: Serine/threonine protein phosphatase Z

Browser: contigA:1516227-1518216+

RNA-seq: read pairs 6457, FPKM 120.3, percentile rank 81.9% (100% = highest expression)

Protein function

Annotation:PPZ1BSerine/threonine protein phosphatase Z
KEGG:K06269PPP1C serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
EGGNOG:0QDCKserine threonine-protein phosphatase
SGD closest match:S000004478PPZ1Serine/threonine-protein phosphatase PP-Z1
CGD closest match:CAL0000189734PPZ1Serine/threonine-protein phosphatase

Protein alignments

%idAln lengthE-value
MIA_05917_186.03%3150.0MIA_05917_1
A0A0J9X6K9_GEOCN76.44%3480.0Serine/threonine-protein phosphatase OS=Geotrichum candidum GN=BN980_GECA04s00373g PE=3 SV=1
Q6C467_YARLI70.61%3136e-171Serine/threonine-protein phosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E29307g PE=3 SV=1
UniRef50_Q6C46770.61%3131e-167Serine/threonine-protein phosphatase n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C467_YARLI
A0A060T908_BLAAD76.37%2921e-170Serine/threonine-protein phosphatase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40568g PE=3 SV=1
PPZ1_YEAST65.48%3365e-166Serine/threonine-protein phosphatase PP-Z1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PPZ1 PE=1 SV=5
A0A167DR91_9ASCO62.64%3643e-164Serine/threonine-protein phosphatase OS=Sugiyamaella lignohabitans GN=PPZ1 PE=3 SV=1
A0A1E3PQN6_9ASCO68.71%3101e-162Serine/threonine-protein phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_21138 PE=3 SV=1
A0A1E4TFY2_9ASCO65.50%3132e-162Serine/threonine-protein phosphatase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31508 PE=3 SV=1
Q59U06_CANAL66.67%3121e-160Serine/threonine-protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PPZ1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0145

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 662

Detailed signature matches

  1. Family IPR011159
    Phosphoprotein phosphatase PPZ/Ppq1
    1. PIRSF000909 (STPPPt...)
  2. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  3. Domain IPR031675
    Serine-threonine protein phosphatase, N-terminal
    1. PF16891 (STPPase_N)
  4. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  5. Domain IPR006186
    Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    1. PS00125 (SER_THR_PH...)
    2. SM00156 (pp2a_7)
    3. PR00114 (STPHPHTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00484_1
MGNTPSKNDHTNISMTPNVVAGHSSSSASTSGSTSEDGGGLDDPICSGNSKTKLMYHNSSAHYSQHQPSPQHAVKTQNSM
HGISPESPSHPRIQVPIDNQLSSLSLGPSALSSPQPSKYPAKASASPNAVTIKNEPSKNYLFANNVGSPYIIGTSNDLQS
PHVASFSSSSSFGEPSSNYFPVEGQRKEASNPNWLHSPSPAIPTGTRRQSIHSTNNELYATGSSVTTNVTLSSSVSSVAT
NSGSSLSSFSQDSPNQSPTIAPIRHSSDASSLSTVTSLNQGKTSTPQQPLTSYKPHSSRKSTPSVIGGPSVETPSKSSGH
KGVSPGARPKQHAVDVNELIQRLIDAGLSSSPPSKKVCISNNEIIGICRAARSIFLSQPTLLELGTPVQVVGDIHGQYGD
LMRVFQLCGMPPASNYLFLGDYVDRGKQSIETILLLLCFKIRYPENVFLLRGNHECASVTRVYGFYDECKRRTSVKVWKT
FVDTFNTFPIAATIGGKIFCVHGGLSPYLNSLDDIRSIQRPTDIPDAGLLSDLLWSDPDGSVTDWRPNDRGISYCFGKSV
VDAFCSKLGFDLVARGHMVVEDGYEFFNHRKLVTVFSAPNYCGEFGNWAAVMSVGKDLLCRFELLKPLDTNGVKKALKNG
RAKERFVGNISTTKAVNLRHNG

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity
GO:0016787 hydrolase activity
GO:0048037 cofactor binding

Cellular Component

None predicted.