Protein

MCA_00408_1

Length
980 amino acids

Gene name: KIN3

Description: Serine/threonine-protein kinase KIN3, homologue in S. cerevisiae probably plays a role in DNA damage response

Browser: contigA:1285869-1288920-

RNA-seq: read pairs 747, FPKM 9.4, percentile rank 25.1% (100% = highest expression)

Protein function

Annotation:KIN3Serine/threonine-protein kinase KIN3, homologue in S. cerevisiae probably plays a role in DNA damage response
KEGG:K20872NEK2 NIMA (never in mitosis gene a)-related kinase 2 [EC:2.7.11.1]
EGGNOG:0PIY3KIN3G2-specific protein kinase
SGD closest match:S000000071KIN3Serine/threonine-protein kinase KIN3
CGD closest match:CAL0000189018KIN3Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_01401_169.51%4100.0MIA_01401_1
A0A0J9X3T6_GEOCN63.97%3834e-166Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA02s00857g PE=4 SV=1
UniRef50_A0A0J9X3T663.97%3839e-163Uncharacterized protein n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3T6_GEOCN
A0A060T8T4_BLAAD64.15%3714e-161ARAD1D10010p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D10010g PE=4 SV=1
A0A161HIP2_9ASCO62.04%3824e-151Serine/threonine protein kinase KIN3 OS=Sugiyamaella lignohabitans GN=KIN3 PE=4 SV=1
A0A1E3PHF2_9ASCO60.88%3632e-153Kinase-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_9001 PE=3 SV=1
Q6C3K5_YARLI57.49%3671e-133YALI0E34067p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E34067g PE=3 SV=1
Q5A5S5_CANAL43.85%3905e-97Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KIN3 PE=3 SV=1
KIN3_YEAST40.21%3734e-81Serine/threonine-protein kinase KIN3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIN3 PE=3 SV=2
A0A1E4TLQ6_9ASCO30.77%2867e-31Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30775 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0683

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 980

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. cd08217 (STKc_Nek2)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd08217
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_00408_1
MSLVAQFEPLEVIGRGSFGLIRKVRRISDGKILARKEISYRQMSAKEKSQLMDEFIILKSLIHPNIVQYYDHDHVVEEHS
VHLYMEYCDGGDLASIIRTCKETGEYVPESLVWSFFTQLVLALYRCHYNCDPPPPGDLFVSSDSNYNPPTPSTVILHRDI
KPDNVFLDQFNTVKLGDFGLAKILDQEHFMANSYVGTPYYMSPEVLRDQPFTPQSDIWSLGCVIYELCAKHPPFQAKSHM
QLAQKIKEGAYPPLPSVYSSTLGKTIAACLNRNFMQRPTTSTLLNLDVMKLCRKDRELGQVRRELEAAQNELQTKEQYLI
TQEEQFMIERENMIQQLQLEQEAQRMQMFQTINDEFNLRVEQEVERRIKMMIEGSQNNVESQEHKTKSMSENNNLQMSPH
ANNGWEMPDVTPMAPGSYNIKFSANDFNSMERNGLQHISAASLSSSLATFSGFPTDNSNILSSPDDVIMTSAQNTPFLQR
NMKVPKTNMEDNNGSNDLSPTANFSSGFIKTPPLKKLLFGNGTNLENKYNLRKLKVGVKSPFINRPNSDDLTSPTLASSY
RRKQLESQKFGTNKASEHSALSSSDNNNNNKQGSNLENSPASFQSAFPSNHSIEDSPTSTKSNNNNNLHFHQLTPSTHQH
QKLSDNFNHHLAAFSNKSSNPNRAIEDVSSNSSISIYSSQSSRRSDSSSSSVENDMTSPLLECTSECNANNNYHSDNNEK
YHRHHQHHQQQVSFGSHVPITYTPATPRERQAPHFQAVYEAKKSIVGSSDFVMGGTMGKVMAIKGPLSSMGRAVVQTSRF
DDDDDDNDNNNENNEDNKKDEYLKTPTNKVQMATLSPTSAAKKKFSALDNYLINANSPTSLKAPSKTKSSNTSPDLGSRP
FYSHPNSSGNVEDSPSRNYENNKQNQQNMLDGISSKKSTTASTIKPLITNQKKNMLNFNTNKNFKDLTGHGGNNSWDENR
GIRDDDIPSPFLKRYERRRV

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.