Protein
MCA_00403_1
Length
174 amino acids
Gene name: IMP2
Description: Mitochondrial inner membrane protease subunit 2
Browser: contigA:1264858-1265383-
RNA-seq: read pairs 220, FPKM 15.5, percentile rank 34.9% (100% = highest expression)
Protein function
| Annotation: | IMP2 | Mitochondrial inner membrane protease subunit 2 | |
|---|---|---|---|
| KEGG: | K09648 | IMP2 | mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-] |
| EGGNOG: | 0PRJJ | FG06221.1 | mitochondrial inner membrane protease subunit |
| SGD closest match: | S000004638 | IMP2 | Mitochondrial inner membrane protease subunit 2 |
| CGD closest match: | CAL0000193849 | IMP2 | Mitochondrial inner membrane protease subunit 2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XBS6_GEOCN | 62.35% | 170 | 3e-81 | Similar to Saccharomyces cerevisiae YMR035W IMP2 Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space OS=Geotrichum candidum GN=BN980_GECA08s03827g PE=4 SV=1 |
| MIA_01461_1 | 58.03% | 193 | 1e-80 | MIA_01461_1 |
| A0A1E3PES0_9ASCO | 58.90% | 163 | 4e-67 | LexA/Signal peptidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84316 PE=4 SV=1 |
| UniRef50_W6MJJ1 | 54.71% | 170 | 5e-62 | Uncharacterized protein n=9 Tax=Saccharomycetales TaxID=4892 RepID=W6MJJ1_9ASCO |
| A0A161HJT0_9ASCO | 56.89% | 167 | 3e-64 | Imp2p OS=Sugiyamaella lignohabitans GN=IMP2 PE=4 SV=1 |
| Q6CF21_YARLI | 53.18% | 173 | 6e-58 | YALI0B10978p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10978g PE=4 SV=1 |
| A0A060T524_BLAAD | 51.55% | 161 | 8e-56 | ARAD1C02596p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C02596g PE=4 SV=1 |
| IMP2_YEAST | 50.68% | 146 | 1e-52 | Mitochondrial inner membrane protease subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IMP2 PE=1 SV=1 |
| A0A1D8PN24_CANAL | 51.01% | 149 | 9e-50 | Mitochondrial inner membrane protease subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IMP2 PE=3 SV=1 |
| A0A1E4TDS8_9ASCO | 45.32% | 139 | 4e-37 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12307 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4902
Protein family membership
- Peptidase S26A, signal peptidase I (IPR000223)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
160
174
Detailed signature matches
no IPR
Unintegrated signatures
-
-
NON_CYTOPLASM... (N...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
-
cd06530 (S26_SPase_I)
Residue annotation
-
Catalytic site cd0...
Protein sequence
>MCA_00403_1 MLRYTTKLALVTLSWIPVAMTFTEHVAHIGRIEGISMKPTLNPDNSLGWTDFVLIWKYGVKNAEKLHVGDVVLLRSPKNP DRILVKRVLGVEGDEIITRSPYPRPTAKIPASHLWVEGDNVFHSIDSNTFGPISVGLVLGKATHVIFPFKRFGAIPSNTS REARLNKLHEINSK
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0008236 serine-type peptidase activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane