Protein

MCA_00386_1

Length
976 amino acids

Gene name: TRZ1

Description: tRNA 3'-end processing endonuclease tRNase Z

Browser: contigA:1193929-1196860+

RNA-seq: read pairs 823, FPKM 10.4, percentile rank 26.6% (100% = highest expression)

Protein function

Annotation:TRZ1tRNA 3'-end processing endonuclease tRNase Z
KEGG:K00784rnz ribonuclease Z [EC:3.1.26.11]
EGGNOG:0PGTVPGUG_02613tRNA processing endoribonuclease
SGD closest match:S000001787TRZ1Ribonuclease Z
CGD closest match:CAL0000186672orf19.5425TRNase Z

Protein alignments

%idAln lengthE-value
MIA_01731_151.92%9380.0MIA_01731_1
A0A0J9XI61_GEOCN41.91%9210.0Similar to Saccharomyces cerevisiae YKR079C TRZ1 tRNA 3'-end processing endonuclease tRNase Z OS=Geotrichum candidum GN=BN980_GECA16s00714g PE=4 SV=1
UniRef50_A0A0J9XI6141.91%9210.0Similar to Saccharomyces cerevisiae YKR079C TRZ1 tRNA 3'-end processing endonuclease tRNase Z n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI61_GEOCN
A0A060T0B4_BLAAD40.05%8040.0ARAD1C11638p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11638g PE=4 SV=1
A0A1E3PRZ3_9ASCO35.95%8404e-159Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4557 PE=4 SV=1
A0A167CBN7_9ASCO35.40%7914e-146Trz1p OS=Sugiyamaella lignohabitans GN=TRZ1 PE=4 SV=1
Q6CH35_YARLI32.73%8222e-120YALI0A13057p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A13057g PE=4 SV=1
RNZ_YEAST32.08%8518e-120Ribonuclease Z OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRZ1 PE=1 SV=1
Q5A7P2_CANAL30.88%8161e-101TRNase Z OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5425 PE=4 SV=1
A0A1E4TFK7_9ASCO29.50%5838e-61Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106916 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0461

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 976

Detailed signature matches

  1. Domain IPR027794
    tRNase Z endonuclease
    1. PF13691 (Lactamase_B_4)
  2. Domain IPR001279
    Metallo-beta-lactamase
    1. PF12706 (Lactamase_B_2)
    2. G3DSA:3.60.15.10
    3. SSF56281 (Metallo-h...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07718 (RNaseZ_ELA...)
  2. mobidb-lite (disord...)

Residue annotation

  1. putative active si...
  2. putative metal bin...
  3. putative metal bin...
  4. putative metal bin...

Protein sequence

>MCA_00386_1
MESVFHHPPAANVISLPDILLPSGKPVTDINELFNNRKAKKAKKVKDPKKQASNNTNEGKKEDDRPFLSSSMKTVFQVLS
HGTSDCRSPSLLLQTEKGEKHLFGRICEGFQRTVSQNHIKFTKLQNIFISGPIEWSSVGGLPGMILTLADQGLDKLALQT
AVSNLPWACATWRNFIFRGRLNFTLKNAEAELYSDKYICVKGVSIYPDSYTHQDYMKNYEKQEEVNKESYEIFRQLFSTL
ENESGTNKGKKSQKQEASDKTGSRSSSPSRLDKNGKKRSPPTGTALAPVAEASLPPINIDPRVSCYIIQVRPTRGKFLVE
KAKALGVPPGVLYSHLTSGQSVVTPEGKTVHPEQVLEPTVINKRSLVIDCPGKEYVNDLINNHDWRQSLHPSTQASNLEM
KNPEASPDHKRIKMASDPEPGYAEPVSTAYHFLGASVDPFHGPYFDWLTDPNSTVFAPDCMHFITHPEYAPDGITLEAAA
ILNMKLRQIFPENFKRLYTADPIKQFPDPETNNYKIYPMYTLGTVSVEPKIAYQTSLQKCNGKVDWPALEEAAGLSQKNA
LDDAQISEMEKKIEEEVPENLRDIEIITLGTGSAAPNKYRNVISTLVRIPSLSSTQNEKSFRSILFDCGENSLWNMKRIY
GPEELNKRVAEIDILYISHLHADHHLGAISFIENWLTSTSATPERTLYVMGPWKYFDFLKEWSQLEHDVSLGRLNFVDNE
SFMIGRGYDNVPVKRSHSRSPSPKGQRLDGKFFQDTGLKAVRTCKAIHCDLSYCVSFEFLLAGADKSTFKVSYSGDTRPT
EFFATKIGYNSDLLIHEATHDNDLEEEAFKKRHSTISEALSISRSMNARYTVLTHFSQRYPKLPNLTGLSEYTLKKHKQR
QEKNAANVRNRRNSKNGSSSPQEVSKSDDEEMKDADTSETTEEQIPQLPVFAFAFDGLHLKLQDIPKQRLKFDRLEKLFD
EVVEMEAIEEEEDKNV

GO term prediction

Biological Process

GO:0008033 tRNA processing

Molecular Function

None predicted.

Cellular Component

None predicted.