MCA_00372_1

Protein

Length

502 amino acids

Gene name: SPE1

Description: Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis

Browser: contigA:1161826-1163335-

RNA-seq: read pairs 3929, FPKM 96.5, percentile rank 78.1% (100% = highest expression)

Protein function

Annotation:		SPE1	Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis
KEGG:	K01581	E4.1.1.17	ornithine decarboxylase [EC:4.1.1.17]
EGGNOG:	0PGWB	ODC	ornithine decarboxylase
SGD closest match:	S000001667	SPE1	Ornithine decarboxylase
CGD closest match:	CAL0000182839	SPE1	Ornithine decarboxylase

Protein alignments

	%id	Aln length	E-value
MIA_01436_1	66.02%	512	0.0	MIA_01436_1
A0A0J9XAY0_GEOCN	62.15%	502	0.0	Similar to Saccharomyces cerevisiae YKL184W SPE1 Ornithine decarboxylase OS=Geotrichum candidum GN=BN980_GECA08s02309g PE=3 SV=1
F2Z6G2_YARLI	56.24%	441	1e-176	YALI0B11330p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11330g PE=3 SV=1
A0A161HJW3_9ASCO	57.04%	426	1e-165	Ornithine decarboxylase SPE1 OS=Sugiyamaella lignohabitans GN=SPE1 PE=3 SV=1
A0A060TJU0_BLAAD	56.45%	434	2e-156	ARAD1D49544p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D49544g PE=3 SV=1
A0A1E3PS77_9ASCO	49.36%	466	1e-155	Ornithine decarboxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48362 PE=3 SV=1
A0A1E4TJF2_9ASCO	51.77%	452	5e-154	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_474 PE=3 SV=1
UniRef50_A0A1E4TJF2	51.77%	452	2e-150	Uncharacterized protein n=1 Tax=Tortispora caseinolytica NRRL Y-17796 TaxID=767744 RepID=A0A1E4TJF2_9ASCO
DCOR_YEAST	46.81%	470	3e-134	Ornithine decarboxylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPE1 PE=1 SV=1
DCOR_CANAL	42.53%	435	7e-115	Ornithine decarboxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPE1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2185

Protein family membership

Ornithine/DAP/Arg decarboxylase (IPR000183)
- Ornithine decarboxylase (IPR002433)

Domains and repeats

Domain
105 - 340
PLP-binding barrel (IPR029066)
Orn/DAP/Arg decarboxylase 2, N-terminal (IPR022644)
Domain
322 - 491
Alanine racemase/group IV decarboxylase, C-terminal (IPR009006)
Orn/DAP/Arg decarboxylase 2, C-terminal (IPR022643)

1 50 100 150 200 250 300 350 400 450 502

Detailed signature matches

IPR000183

Ornithine/DAP/Arg decarboxylase
1. PR01179 (ODADCRBXLASE)
  
  328 - 347
  
  PRINTS
  PR01179 (ODADCRBXLASE)
  
  127 - 145
  
  PRINTS
  PR01179 (ODADCRBXLASE)
  
  249 - 262
  
  PRINTS
  PR01179 (ODADCRBXLASE)
  
  147 - 159
  
  PRINTS
  PR01179 (ODADCRBXLASE)
  
  468 - 481
  
  PRINTS
  PR01179 (ODADCRBXLASE)
IPR002433

Ornithine decarboxylase
1. PR01182 (ORNDCRBXLASE)
  
  99 - 123
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  455 - 468
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  371 - 384
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  169 - 193
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  199 - 221
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  125 - 152
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
  
  434 - 444
  
  PRINTS
  PR01182 (ORNDCRBXLASE)
IPR029066

PLP-binding barrel
1. G3DSA:3.20.20.10
  
  109 - 331
  
  GENE3D
  G3DSA:3.20.20.10 (G3DSA:3.20.20.10)
2. SSF51419 (PLP-bindi...)
  
  105 - 340
  
  SUPERFAMILY
  SSF51419 (PLP-binding barrel)
IPR022644

Orn/DAP/Arg decarboxylase 2, N-terminal
1. PF02784 (Orn_Arg_deC_N)
  
  107 - 338
  
  Pfam
  PF02784 (Orn_Arg_deC_N)
IPR009006

Alanine racemase/group IV decarboxylase, C-terminal
1. SSF50621 (Alanine r...)
  
  322 - 395
  
  SUPERFAMILY
  SSF50621 (Alanine racemase C-terminal domain-like)
  
  425 - 491
  
  SUPERFAMILY
  SSF50621 (Alanine racemase C-terminal domain-like)
2. G3DSA:2.40.37.10
  
  332 - 491
  
  GENE3D
  G3DSA:2.40.37.10 (G3DSA:2.40.37.10)
IPR022643

Orn/DAP/Arg decarboxylase 2, C-terminal
1. PF00278 (Orn_DAP_Ar...)
  
  335 - 468
  
  Pfam
  PF00278 (Orn_DAP_Arg_deC)
IPR022653

Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
1. PS00878 (ODR_DC_2_1)
  
  127 - 145
  
  PROSITE patterns
  PS00878 (ODR_DC_2_1)

no IPR

Unintegrated signatures

cd00622 (PLPDE_III_ODC)

98 - 490

CDD
cd00622 (PLPDE_III_ODC)

Residue annotation

dimer interface cd...

99D

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

130K

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

151A

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

152S

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

154N

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

155E

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

177A

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

182R

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

195D

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

198D

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

202K

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

229I

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

230K

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

231Y

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

348V

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

350R

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

351R

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

366M

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

368Y

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

370N

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

373V

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

374Y

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

382F

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

384H

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

437G

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

439T

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

441D

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

444D

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

474A

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

476T

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

478F

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

479N

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

480G

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)

483G

dimer interface
99D, 130K, 151A, 152S, 154N, 155E, 177A, 182R, 195D, 198D, 202K, 229I, 230K, 231Y, 348V, 350R, 351R, 366M, 368Y, 370N, 373V, 374Y, 382F, 384H, 437G, 439T, 441D, 444D, 474A, 476T, 478F, 479N, 480G, 483G
CDD
cd00622 (PLPDE_III_ODC)
active site cd00622

128A

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

130K

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

149D

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

215R

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

258H

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

261S

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

298G

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

299G

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

331E

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

332P

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

333G

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

334R

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

383D

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

440C

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

470Y

active site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 383D, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)
pyridoxal 5'-phosp...

128A

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

130K

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

149D

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

215R

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

258H

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

261S

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

298G

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

299G

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

331E

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

332P

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

333G

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

334R

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

440C

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)

470Y

pyridoxal 5'-phosphate (PLP) binding site
128A, 130K, 149D, 215R, 258H, 261S, 298G, 299G, 331E, 332P, 333G, 334R, 440C, 470Y
CDD
cd00622 (PLPDE_III_ODC)
catalytic residues...

130K

catalytic residues
130K, 440C
CDD
cd00622 (PLPDE_III_ODC)

440C

catalytic residues
130K, 440C
CDD
cd00622 (PLPDE_III_ODC)
substrate binding ...

382F

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

383D

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

440C

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

441D

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

470Y

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

478F

substrate binding site
382F, 383D, 440C, 441D, 470Y, 478F
CDD
cd00622 (PLPDE_III_ODC)

Protein sequence

>MCA_00372_1
MSPFLLDTDIIGEDVVKIPISNNNPLLEQKTEESSVQVREVDFSSSSSIATLADYNDDADLKSVSPLIDHSMSQRLVGAA
LKSHINTVDIDECPAGGEDSFFVADLGRVYNQYKRWMACLPRIEPFYAMKCNNDPKVLGLLSSLGLGFDCASKNEIDTIV
SLGVNPKKIVYAHPCKALSYIRHASNVGVEMMTFDNSDELLKCKRAYPNAKLLLRIMTDDSKSLCQFSIKYGASMDNAYQ
LLKLGKELGLNIIGVSFHVGSGASDPSAFVDAVTNARQVFDWAEELGMPKMTVLDVGGGFVDETFEETAAVLGPCIEQLF
PVESGVRVIAEPGRYFVSSAFTLAVNVVGRRVTTKNIGDKTHPHLMLYINDGVYANMNCIIFDHQEPVPKILSKKQTFMY
NEGASGPDFSVYSDDGSEVSSVSSENSSSEVEVSIWGPTCDGIDVITKGSMLPDSVDVGDWLYFTEFGAYTLSAATTFNG
FNGDCKVIYVSSEPNVKRYVSF

GO term prediction

Biological Process

GO:0006596 polyamine biosynthetic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features