Protein
MCA_00370_1
Length
316 amino acids
Gene name: ADE1
Description: Phosphoribosylaminoimidazole-succinocarboxamide synthase
Browser: contigA:1159207-1160158+
RNA-seq: read pairs 4682, FPKM 182.5, percentile rank 87.0% (100% = highest expression)
Protein function
| Annotation: | ADE1 | Phosphoribosylaminoimidazole-succinocarboxamide synthase | |
|---|---|---|---|
| KEGG: | K01923 | purC | phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] |
| EGGNOG: | 0PFD3 | ADE1 | phosphoribosyl-aminoimidazole-succinocarboxamide synthase |
| SGD closest match: | S000000070 | ADE1 | Phosphoribosylaminoimidazole-succinocarboxamide synthase |
| CGD closest match: | CAL0000196632 | ADE1 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01434_1 | 85.76% | 316 | 0.0 | MIA_01434_1 |
| A0A0J9X3U5_GEOCN | 77.00% | 313 | 3e-173 | Similar to Saccharomyces cerevisiae YAR015W ADE1 N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase OS=Geotrichum candidum GN=BN980_GECA02s00868g PE=3 SV=1 |
| A0A1E3PRE7_9ASCO | 68.57% | 315 | 2e-157 | Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45523 PE=3 SV=1 |
| A0A060TER6_BLAAD | 64.74% | 312 | 6e-147 | ARAD1D09988p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09988g PE=3 SV=1 |
| A0A167C219_9ASCO | 65.92% | 314 | 1e-144 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase OS=Sugiyamaella lignohabitans GN=ADE1 PE=3 SV=1 |
| PUR7_YEAST | 65.08% | 315 | 1e-143 | Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE1 PE=1 SV=2 |
| UniRef50_P27616 | 65.08% | 315 | 2e-140 | Phosphoribosylaminoimidazole-succinocarboxamide synthase n=237 Tax=Fungi TaxID=4751 RepID=PUR7_YEAST |
| A0A1E4TF08_9ASCO | 65.52% | 319 | 1e-141 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_105199 PE=3 SV=1 |
| Q6C3Q2_YARLI | 63.23% | 310 | 2e-138 | YALI0E33033p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E33033g PE=3 SV=1 |
| A0A1D8PRQ1_CANAL | 61.54% | 312 | 1e-123 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADE1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0579
Protein family membership
Domains and repeats
-
Domain
1
50
100
150
200
250
316
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
ATP binding site c...
-
active site cd01414
-
substrate binding ...
Protein sequence
>MCA_00370_1 MSAVTSTDLKGALPLLAQGKVRDIYTVDESSLLFVATDRISAYDVIMENGIPDKGKLLTKISEFWFKLLGDEVKTHLVGP KFEEDDEALFKLLPASLSEDASIKSQLIGRSLLVNKFKLIPLEVIVRGYITGSAWSEYKKSGTVHGIKVAEGLQESQEFE TPLYTPSTKAEQGEHDENIHPSKAVEILGGDEKLAKEIEDLAIRLYTKARDYAKEKGIIIADTKFEFGYIENDDGSKTLV LVDEVLTPDSSRFWRADTYKIGQGQDSYDKQFLRNWLTDNKLKGKEGVKIPQEIVENTRKKYIEAYEAITGEKYSS
GO term prediction
Biological Process
GO:0006164 purine nucleotide biosynthetic process
Molecular Function
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Cellular Component
None predicted.