Protein
MCA_00369_1
Length
250 amino acids
Gene name: ISA2
Description: Iron-sulfur assembly protein 2; Protein required for maturation of mitochondrial [4Fe-4S] proteins
Browser: contigA:1157775-1158528+
RNA-seq: read pairs 1438, FPKM 70.8, percentile rank 73.0% (100% = highest expression)
Protein function
| Annotation: | ISA2 | Iron-sulfur assembly protein 2; Protein required for maturation of mitochondrial [4Fe-4S] proteins | |
|---|---|---|---|
| EGGNOG: | 0PPQS | ISA2 | protein required for |
| SGD closest match: | S000006271 | ISA2 | Iron-sulfur assembly protein 2 |
| CGD closest match: | CAL0000191195 | ISA2 | Isa2p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01432_1 | 80.69% | 145 | 9e-86 | MIA_01432_1 |
| A0A0J9X2Z8_GEOCN | 72.97% | 148 | 1e-77 | Similar to Saccharomyces cerevisiae YPR067W ISA2 Protein required for maturation of mitochondrial and cytosolic Fe/S proteins OS=Geotrichum candidum GN=BN980_GECA02s00879g PE=4 SV=1 |
| A0A161HIS1_9ASCO | 62.32% | 138 | 4e-58 | Isa2p OS=Sugiyamaella lignohabitans GN=ISA2 PE=4 SV=1 |
| UniRef50_A0A161HIS1 | 62.32% | 138 | 1e-54 | Isa2p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HIS1_9ASCO |
| Q6C3Q0_YARLI | 58.96% | 134 | 5e-52 | YALI0E33077p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E33077g PE=4 SV=1 |
| A0A060T8B8_BLAAD | 65.71% | 140 | 2e-50 | ARAD1D09944p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09944g PE=4 SV=1 |
| A0A1E3PFZ3_9ASCO | 57.04% | 135 | 1e-49 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83816 PE=4 SV=1 |
| A0A1E4THM3_9ASCO | 61.11% | 126 | 1e-48 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2959 PE=4 SV=1 |
| Q5ADN0_CANAL | 51.24% | 121 | 9e-34 | Isa2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ISA2 PE=4 SV=1 |
| ISA2_YEAST | 42.54% | 134 | 2e-24 | Iron-sulfur assembly protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISA2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9938
Predicted cleavage: 82
Protein family membership
- FeS cluster insertion protein (IPR016092)
Domains and repeats
-
Domain
1
50
100
150
200
250
250
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_00369_1 MYRISSTCITNATKFSSTNSISKRSLSYITGTHKHLTRNMILSHSISLASSTSYKKLGDSSAVNSSSQSSNIPKSFSNSR PSTTSASTNSSSSMQSNLQNDGPRRKPTLGADVEDTTKIINPVKSESGDILKVKISQRAANKLKQINESDNKPNQILRIL VESGGCHGYQYVLGLKDSSTIDPEEDCIFERDGAQFVIDSTSLQILRDSTIDYTTELIGSQFKVVNSPYTKSSCGCGSSF DFDPSAIPTN
GO term prediction
Biological Process
GO:0097428 protein maturation by iron-sulfur cluster transfer
Molecular Function
GO:0005198 structural molecule activity
GO:0051536 iron-sulfur cluster binding
Cellular Component
None predicted.