Protein
MCA_00319_1
Length
289 amino acids
Gene name: PTH2
Description: Peptidyl-tRNA hydrolase 2
Browser: contigA:964390-965260+
RNA-seq: read pairs 1206, FPKM 51.4, percentile rank 66.0% (100% = highest expression)
Protein function
| Annotation: | PTH2 | Peptidyl-tRNA hydrolase 2 | |
|---|---|---|---|
| KEGG: | K04794 | PTH2 | peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] |
| EGGNOG: | 0PNRQ | PGUG_01675 | Peptidyl-tRNA hydrolase |
| SGD closest match: | S000000153 | PTH2 | Peptidyl-tRNA hydrolase 2 |
| CGD closest match: | CAL0000194649 | CAALFM_CR01570WA | Aminoacyl-tRNA hydrolase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X4D9_GEOCN | 75.78% | 128 | 7e-58 | Similar to Saccharomyces cerevisiae YBL057C PTH2 One of two (See also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases OS=Geotrichum candidum GN=BN980_GECA02s04245g PE=4 SV=1 |
| UniRef50_A0A0J9X4D9 | 75.78% | 128 | 1e-54 | Similar to Saccharomyces cerevisiae YBL057C PTH2 One of two (See also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4D9_GEOCN |
| MIA_01639_1 | 77.95% | 127 | 3e-55 | MIA_01639_1 |
| A0A060T3W3_BLAAD | 68.75% | 128 | 4e-54 | ARAD1C43384p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43384g PE=4 SV=1 |
| A0A167FI50_9ASCO | 65.62% | 128 | 3e-49 | Pth2p OS=Sugiyamaella lignohabitans GN=PTH2 PE=4 SV=1 |
| A0A1E4TE06_9ASCO | 58.87% | 124 | 6e-40 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1711 PE=4 SV=1 |
| A0A1E3PK62_9ASCO | 62.71% | 118 | 2e-38 | PTH2-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83340 PE=4 SV=1 |
| Q5A9C1_CANAL | 59.84% | 122 | 7e-35 | Aminoacyl-tRNA hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR01570WA PE=4 SV=1 |
| Q6C4E6_YARLI | 63.48% | 115 | 3e-33 | YALI0E27412p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27412g PE=4 SV=1 |
| PTH2_YEAST | 59.84% | 122 | 4e-33 | Peptidyl-tRNA hydrolase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTH2 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7069
Predicted cleavage: 69
Protein family membership
- Peptidyl-tRNA hydrolase, PTH2 (IPR002833)
Domains and repeats
-
Domain
1
50
100
150
200
250
289
Detailed signature matches
-
-
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SSF102462 (Peptidyl...)
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no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Residue annotation
-
dimer interface cd...
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putative active si...
Protein sequence
>MCA_00319_1 MANSNSFSTNPTALSSPIVLSGLAVTGLVGFLCGVLWTNQGRRGLNFFSSKKARNSKKEARRRSKKRAHSKKPSKKNNKS NKSSPISDDKKDQENSSKSSQSNSPEPGKTILELDDKDLAEEGDDDYVYSGTPSSTASSDDDYEDEDDSEDDYSDLEDPR YDASPGAFAFTQEQCKMVLVIRTDLHMTKGKIAAQCAHAALACFKSIQRSNPEILARWERFGQAKITLQVKSEEELQLLQ AKAVSLDVTARLVRDAGRTQIAAGSATVLGLGPAPISVIDKITGGLKLY
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0004045 aminoacyl-tRNA hydrolase activity
Cellular Component
None predicted.