Protein

MCA_00306_1

Length
139 amino acids


Description: 5-hydroxyisourate hydrolase

Browser: contigA:936906-937326+

RNA-seq: read pairs 915, FPKM 80.8, percentile rank 75.4% (100% = highest expression)

Protein function

Annotation:5-hydroxyisourate hydrolase
KEGG:K07127uraH 5-hydroxyisourate hydrolase [EC:3.5.2.17]
EGGNOG:0PRX6FG09890.15-hydroxyisourate hydrolase
CGD closest match:CAL0000201199orf19.3633Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_01654_164.75%1391e-52MIA_01654_1
A0A0J9XEJ3_GEOCN54.17%1441e-435-hydroxyisourate hydrolase OS=Geotrichum candidum GN=BN980_GECA13s00626g PE=3 SV=1
A0A1E3PQ85_9ASCO47.74%1557e-375-hydroxyisourate hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49899 PE=3 SV=1
Q6C0Q5_YARLI44.83%1452e-335-hydroxyisourate hydrolase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F22605g PE=3 SV=1
UniRef50_Q6C0Q544.83%1456e-305-hydroxyisourate hydrolase n=3 Tax=Dipodascaceae TaxID=34353 RepID=Q6C0Q5_YARLI
A0A060TID4_BLAAD46.43%1407e-335-hydroxyisourate hydrolase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45672g PE=3 SV=1
A0A167FZ94_9ASCO44.44%1447e-305-hydroxyisourate hydrolase OS=Sugiyamaella lignohabitans GN=AWJ20_3538 PE=3 SV=1
Q59Y16_CANAL39.02%1643e-28Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3633 PE=4 SV=1
A0A1E4TJ85_9ASCO41.01%1393e-235-hydroxyisourate hydrolase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21694 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0887

Protein family membership

Domains and repeats

1 20 40 60 80 100 120 139

Detailed signature matches

    1. PF00576 (Transthyretin)
    2. SSF49472 (Transthyr...)
    3. SM00095 (transthy-fin)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd05822 (TLP_HIUase)

Residue annotation

  1. active site cd05822
  2. homotetramer inter...

Protein sequence

>MCA_00306_1
MSKHPITCHVLDTASGKPAAGIECTLYLLSTSTDSLSSISNSTPEPLGTATTNDDGRIMTWTFSSSSKAHSAVSKWDDHV
ITPGVYKIKFETSPYFEKKGSSTFFPFVEVVFKINNPPDAHYHVPLLLSNFSYSTYRGS

GO term prediction

Biological Process

GO:0006144 purine nucleobase metabolic process

Molecular Function

GO:0033971 hydroxyisourate hydrolase activity

Cellular Component

None predicted.