Protein

MCA_00297_1

Length
554 amino acids

Gene name: PGI1

Description: Glucose-6-phosphate isomerase

Browser: contigA:912200-913865-

RNA-seq: read pairs 47618, FPKM 1060.1, percentile rank 96.7% (100% = highest expression)

Protein function

Annotation:PGI1Glucose-6-phosphate isomerase
KEGG:K01810GPI glucose-6-phosphate isomerase [EC:5.3.1.9]
EGGNOG:0PF7SPGI1glucose-6-phosphate isomerase
SGD closest match:S000000400PGI1Glucose-6-phosphate isomerase
CGD closest match:CAL0000197690PGI1Glucose-6-phosphate isomerase

Protein alignments

%idAln lengthE-value
MIA_01340_182.82%5530.0MIA_01340_1
A0A060T9M5_BLAAD80.36%5500.0Glucose-6-phosphate isomerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38940g PE=3 SV=1
A0A167CML7_9ASCO79.82%5500.0Glucose-6-phosphate isomerase OS=Sugiyamaella lignohabitans GN=PGI1 PE=3 SV=1
S4SV97_GEOCN79.82%5500.0Glucose-6-phosphate isomerase OS=Geotrichum candidum GN=Pgi1 PE=3 SV=1
A0A1E3PRM3_9ASCO77.82%5500.0Glucose-6-phosphate isomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39474 PE=3 SV=1
G6PI_YEAST77.08%5540.0Glucose-6-phosphate isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PGI1 PE=1 SV=3
UniRef50_P1270977.08%5540.0Glucose-6-phosphate isomerase n=1332 Tax=root TaxID=1 RepID=G6PI_YEAST
G6PI_CANAL77.41%5490.0Glucose-6-phosphate isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PGI1 PE=1 SV=2
A0A1E4TH02_9ASCO75.27%5460.0Glucose-6-phosphate isomerase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_115760 PE=3 SV=1
Q6C2I1_YARLI74.82%5480.0Glucose-6-phosphate isomerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07711g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3239

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 554

Detailed signature matches

  1. Family IPR001672
    Phosphoglucose isomerase (PGI)
    1. PR00662 (G6PISOMERASE)
    2. PS51463 (P_GLUCOSE_...)
    3. PF00342 (PGI)
    4. MF_00473 (G6P_isome...)
  2. Domain IPR035476
    Phosphoglucose isomerase, SIS domain 1
    1. cd05015 (SIS_PGI_1)
  3. Domain IPR035482
    Phosphoglucose isomerase, SIS domain 2
    1. cd05016 (SIS_PGI_2)
  4. Domain IPR023096
    Phosphoglucose isomerase, C-terminal
    1. G3DSA:1.10.13...
  5. SITE IPR018189
    Phosphoglucose isomerase, conserved site
    1. PS00765 (P_GLUCOSE_...)
    2. PS00174 (P_GLUCOSE_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. SSF53697 (SIS domain)

Residue annotation

  1. active site cd05015
  2. dimer interface cd...
  3. dimer interface cd...
  4. active site cd05016

Protein sequence

>MCA_00297_1
MTSNATFNQTTDLASWSKLQSLYDTKGKSLKVSDEFQSNKSRFQEFSRTFTNFDGSKILFDFSKNIIDKEILSALIELAN
EAKVEDLRKALFAGDHINFTEDRAVYHMALRNIAGRPMKVDGKDTAPEVKSVLAHMKEFSDEVRSGKWTGYTGKKITDVV
NIGIGGSDLGPVMVTEALKPYASDDLSVHFVSNIDGTHIAETLKKLNPETTLFLIASKTFTTAETTTNAKSAKKWFLATA
KDEAHIAKHFAALSTNAKEVAAFGIDTKNMFGFESWVGGRYSVWSAIGLSIAIYIGYDNFEQFLKGAEAVDKHFVETPLE
QNIPVLGALLTIWYNNFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKSVNRANEFVKYETGTILFGEPATNSQHSFFQ
LVHQGTKLIPADFILAAQSHNPIENNLHQRMLASNFFAQAEALMVGKPKAVVEAEGTKSELVNHKIFQGNRPTTSILVQK
VTPASLGALIAYYEHVTFVEGAIWNINSFDQWGVELGKVLAKVIGKELEDSSEVSTHDGSTQGLINQFKKWAEY

GO term prediction

Biological Process

GO:0006094 gluconeogenesis
GO:0006096 glycolytic process

Molecular Function

GO:0004347 glucose-6-phosphate isomerase activity

Cellular Component

None predicted.