Protein

MCA_00242_1

Length
463 amino acids

Gene name: SSL1

Description: Subunit of the core form of RNA polymerase transcription factor TFIIH

Browser: contigA:744977-746369+

RNA-seq: read pairs 323, FPKM 8.6, percentile rank 23.5% (100% = highest expression)

Protein function

Annotation:SSL1Subunit of the core form of RNA polymerase transcription factor TFIIH
KEGG:K03142TFIIH2 transcription initiation factor TFIIH subunit 2
EGGNOG:0PG5MFG06002.1Suppressor of stem-loop protein 1
SGD closest match:S000003995SSL1Suppressor of stem-loop protein 1
CGD closest match:CAL0000176995orf19.1457TFIIH/NER complex subunit

Protein alignments

%idAln lengthE-value
MIA_05748_178.66%4170.0MIA_05748_1
A0A0J9XAR6_GEOCN74.33%4130.0Similar to Saccharomyces cerevisiae YLR005W SSL1 Component of the core form of RNA polymerase transcription factor TFIIH OS=Geotrichum candidum GN=BN980_GECA07s03552g PE=4 SV=1
A0A1E3PKD1_9ASCO63.68%4130.0Component of the core form of RNA polymerase transcription factor OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82732 PE=4 SV=1
A0A167EKC1_9ASCO61.35%4140.0TFIIH/NER complex subunit SSL1 OS=Sugiyamaella lignohabitans GN=SSL1 PE=4 SV=1
Q6C7M6_YARLI57.31%4243e-179YALI0D26862p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26862g PE=4 SV=1
UniRef50_Q6C7M657.31%4248e-176YALI0D26862p n=9 Tax=Saccharomycetales TaxID=4892 RepID=Q6C7M6_YARLI
SSL1_YEAST59.20%4025e-174Suppressor of stem-loop protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSL1 PE=1 SV=1
A0A060T899_BLAAD53.59%4187e-150ARAD1C27742p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27742g PE=4 SV=1
A0A1E4TEX5_9ASCO52.94%4083e-146Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_105044 PE=4 SV=1
A0A1D8PGC3_CANAL46.68%4674e-127TFIIH/NER complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1457 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0095

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 463

Detailed signature matches

  1. Family IPR012170
    TFIIH subunit Ssl1/p44
    1. PIRSF015919 (TFIIH_...)
    2. TIGR00622
  2. Domain IPR002035
    von Willebrand factor, type A
    1. SSF53300 (vWA-like)
    2. SM00327 (VWA_4)
    3. G3DSA:3.40.50...
    4. PS50234 (VWFA)
  3. Domain IPR007198
    Ssl1-like
    1. PF04056 (Ssl1)
  4. Domain IPR004595
    TFIIH C1-like domain
    1. PF07975 (C1_4)
    2. SM01047 (C1_4_2)
  5. Domain IPR013087
    Zinc finger C2H2-type
    1. PS00028 (ZINC_FINGE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57889 (Cysteine-...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00242_1
MNDSDDDYIDDSDLKRPNKKAKTKDGAKAKPTAKNSSGFSSIQSLKSANGGYAWEDEYHRSWDIVMEDDGDNLEGVVAGM
VEASKKKRIVKAAIPFQRGIIRNFVLILDLSFAMLEKDLLPNRYRLMLNYTIEFVKEFYDQTPISQLAIIGMRDGLAVLI
SDLSGSPHNHLTALQNLLNNEEPKGDPSLQNALEMARGLLYNVPFHATKEVLIIFGALFSNDPGDIHQTINGLVNDKIRV
QVIGLAAQVAICKELSMKTNFGDESSYGIILNDVHFKELLHEFTTPLAVNKLSTQNSSTLVKMGFPSRISEVSSTFCSCH
SKITRGGYICPRCYAKVCNLPSQCPCCDLTLVLSTHLARSYHHLFPLKPYLEVPQKFAYLHDSCFSCQTPFPNYETIPKD
SNTSSRYSCPDCRNFFCIDCDLYAHETLHNCAGCESKLIQPELVAKPSVKLTFSSTKQTSTSS

GO term prediction

Biological Process

GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

GO:0000439 core TFIIH complex