Protein

MCA_00228_1

Length
652 amino acids

Gene name: SRP72

Description: Signal recognition particle subunit SRP72

Browser: contigA:707267-709226+

RNA-seq: read pairs 2781, FPKM 52.6, percentile rank 66.5% (100% = highest expression)

Protein function

Annotation:SRP72Signal recognition particle subunit SRP72
KEGG:K03108SRP72 signal recognition particle subunit SRP72
EGGNOG:0PIXSSRP72Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity)
SGD closest match:S000006131SRP72Signal recognition particle subunit SRP72
CGD closest match:CAL0000185251orf19.5516Signal recognition particle subunit SRP72

Protein alignments

%idAln lengthE-value
MIA_01276_149.26%6055e-172MIA_01276_1
A0A0J9XDW6_GEOCN36.82%6115e-108Signal recognition particle subunit SRP72 OS=Geotrichum candidum GN=BN980_GECA11s01583g PE=3 SV=1
UniRef50_A0A0J9XDW636.82%6111e-104Signal recognition particle subunit SRP72 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDW6_GEOCN
A0A167DBF9_9ASCO31.18%6672e-62Signal recognition particle subunit SRP72 OS=Sugiyamaella lignohabitans GN=SRP72 PE=3 SV=1
A0A1E3PPH7_9ASCO29.92%5951e-62Signal recognition particle subunit SRP72 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49648 PE=3 SV=1
A0A060TC57_BLAAD30.34%6239e-62Signal recognition particle subunit SRP72 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33462g PE=3 SV=1
F2Z620_YARLI27.90%6201e-31Signal recognition particle subunit SRP72 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E34309g PE=3 SV=1
A0A1D8PPX2_CANAL30.47%2793e-23Signal recognition particle subunit SRP72 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5516 PE=3 SV=1
A0A1E4TIE7_9ASCO24.96%5731e-17Signal recognition particle subunit SRP72 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_71127 PE=3 SV=1
SRP72_YEAST25.20%2546e-09Signal recognition particle subunit SRP72 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRP72 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5050

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 100 200 300 400 500 600 652

Detailed signature matches

  1. Family IPR026270
    Signal recognition particle, SRP72 subunit
    1. PIRSF038922 (SRP72)
  2. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  3. Domain IPR013699
    Signal recognition particle, SRP72 subunit, RNA-binding
    1. PF08492 (SRP72)
  4. Repeat IPR031545
    Putative TPR-like repeat
    1. PF17004 (SRP_TPR_like)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00228_1
MVKNTKSTKNTTLTELVSQLSVYSQKDEYKGIVSTATSILKQSPNDKNALDTLVSAYIKHDRYSDFYKYFENNKELQQSY
LLEYGYALYRLGYHKELTSLIGSREERGFRHLLAQSYYKQGQIRKAKEIYDTIINTPNQVEFEDHDLSVNERAIIAQLKL
LESSTDCQITSISSPKSYDQLFNDALIAIANLDYTTALDLLSNAKVLCQNTSYAPEEMVSEITPILFQASLVQLKLNKPS
DALEILNSIDYENLRDPAMKYLIYTLKLSLKKNDEELSNPYKAIAFLDKAANYSAIQSQFVPLQRQTLNNNRFLLELASG
KSVENLIKSQSKLDTPAFNSLQAYAYLTRYTNNTQSNTEQMKALNKLYSVKKTNVALAFLIAQIYANNDSYSLAAIAISD
YIKNTKEKNPEQAFAPGVIAALSSLYTLAGRESCAIPFIEEAVTYWSKNASEVMDNNQLQILFADSSYLLATSPALKLVS
DTLENLYKQDPSNIVVISGLLGLGDPEISQKYSKHENQLISIQEATRGIDAKLIASSGLEPLLKKRAISSLEQGKVSKGP
AKKKKMGKLPKNYDESKTPDPERWIPLKDRSTYKPPKAKGKKKVLASTQGGQADESLDLASSSTTSTAKTTSSSKSKAKA
KNIKKKKGKGRK

GO term prediction

Biological Process

GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Molecular Function

GO:0005515 protein binding
GO:0008312 7S RNA binding

Cellular Component

GO:0048500 signal recognition particle