Protein

MCA_00183_1

Length
578 amino acids

Browser: contigA:547843-549580+

RNA-seq: read pairs 594, FPKM 12.7, percentile rank 30.3% (100% = highest expression)

Protein function

KEGG:K05302SETD6 N-lysine methyltransferase SETD6 [EC:2.1.1.-]
EGGNOG:0PI4FPGUG_03343SET domain-containing protein
SGD closest match:S000002665RKM4Ribosomal lysine N-methyltransferase 4
CGD closest match:CAL0000193221RMS1Ribosomal lysine N-methyltransferase

Protein alignments

%idAln lengthE-value
MIA_01362_142.41%6065e-133MIA_01362_1
A0A060T865_BLAAD48.33%3606e-99ARAD1D01210p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D01210g PE=4 SV=1
UniRef50_A0A060T86548.33%3602e-95ARAD1D01210p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T865_BLAAD
Q6C037_YARLI47.84%3708e-96YALI0F28061p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F28061g PE=4 SV=1
A0A167CBZ7_9ASCO45.74%3763e-94Rkm4p OS=Sugiyamaella lignohabitans GN=RKM4 PE=4 SV=1
A0A0J9X5J3_GEOCN37.21%5674e-93Similar to Saccharomyces cerevisiae YDR257C RKM4 Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (Lysine 55) OS=Geotrichum candidum GN=BN980_GECA03s05873g PE=4 SV=1
A0A1E3PKN5_9ASCO34.27%5724e-83SET domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41974 PE=4 SV=1
A0A1E4TFF4_9ASCO43.14%3063e-72Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2133 PE=4 SV=1
A0A1D8PNN9_CANAL36.30%4057e-60Ribosomal lysine N-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RMS1 PE=4 SV=1
RKM4_YEAST36.88%3857e-59Ribosomal lysine N-methyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RKM4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0159

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 578

Detailed signature matches

  1. Family IPR011383
    N-lysine methyltransferase SETD6
    1. PIRSF011771 (RMS1_SET)
  2. Domain IPR001214
    SET domain
    1. PF00856 (SET)
    2. PS50280 (SET)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.90.14...
  3. SSF82199 (SET domain)
  4. mobidb-lite (disord...)

Protein sequence

>MCA_00183_1
MTTDSGDFKVKTDNFVNWLKERKVEISPKIAVHDYRSAHQGRGVIALEDIEEGEVLFTIPRSSILAVDSVNPELTPEISK
LFKESPLVKQLDTWMALILYMMIRIKDDEFRPYYDVLPQKLNTLMYWDEKEVKELLKGSTVVDRIGKEGAEESYHNLLKP
IFEENKEFFKDIDTSIEQYHRMGSLIMAYSFDVEKVTSEENEEEDEDEDEEEDETVKAMVPLADILNAHTRLCNANLFHE
DGFLEMRAIKPIPANTQVYNTYGDLPNSDLLRRYGYVETGGNEFDVTEIKTESILEAFIKIFNSEEEKEDSKKQITLDFL
KQGLETLESWQEEADYFSPEGEWAEFVDDSYDIPVTGIAPIELQVLISFLVLYVLDHVTKKKTSESLFLHHYKDSKAATI
DGPEDKTRKKRMRHKLLKLFVKNAKGGKKSKTHEENEEGKEEEEEEKLITPIMFKESLPVYRTICESRKQDYSPEIVEAA
KQNPNPSQVEDVFLTHEEMAKELLTGEVRILDRLLNAVSEASKESDNDSKYLVDGHEYLSKERERLEAEAKERKAAAREI
KKKRQGEDGKADKKKKRK

GO term prediction

Biological Process

GO:0018026 peptidyl-lysine monomethylation

Molecular Function

GO:0005515 protein binding
GO:0016279 protein-lysine N-methyltransferase activity

Cellular Component

None predicted.