Protein

MCA_00178_1

Length
1,350 amino acids

Gene name: OXP1

Description: 5-oxoprolinase

Browser: contigA:523125-527296+

RNA-seq: read pairs 3445, FPKM 31.5, percentile rank 54.0% (100% = highest expression)

Protein function

Annotation:OXP15-oxoprolinase
KEGG:K01469OPLAH 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
EGGNOG:0PGSZPGUG_016635-oxoprolinase
SGD closest match:S000001698OXP15-oxoprolinase
CGD closest match:CAL0000190727HYU15-oxoprolinase

Protein alignments

%idAln lengthE-value
MIA_01369_174.35%13450.0MIA_01369_1
A0A0J9XB25_GEOCN70.65%13460.0Similar to Saccharomyces cerevisiae YKL215C OXP1 5-oxoprolinase OS=Geotrichum candidum GN=BN980_GECA08s02408g PE=4 SV=1
A0A060T936_BLAAD68.31%13190.0ARAD1D08404p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D08404g PE=4 SV=1
A0A1E3PFM3_9ASCO64.61%13620.0Hydantoinase B/oxoprolinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43176 PE=4 SV=1
A0A167FWP6_9ASCO67.41%13070.0Oxp1p OS=Sugiyamaella lignohabitans GN=OXP1 PE=4 SV=1
Q6C7A4_YARLI63.72%13450.0YALI0E02398p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E02398g PE=4 SV=2
UniRef50_T0LBC756.75%13110.0Hydantoinase B/oxoprolinase n=3 Tax=leotiomyceta TaxID=716546 RepID=T0LBC7_COLGC
A0A1D8PGR6_CANAL54.55%13180.05-oxoprolinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HYU1 PE=4 SV=1
A0A1E4TJP7_9ASCO54.88%13230.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_538 PE=4 SV=1
OPLA_YEAST53.21%13250.05-oxoprolinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OXP1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0751

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1350

Detailed signature matches

  1. Family IPR002821
    Hydantoinase/oxoprolinase
    1. PF01968 (Hydantoina...)
  2. Family IPR003692
    Hydantoinase B/oxoprolinase
    1. PF02538 (Hydantoina...)
  3. Domain IPR008040
    Hydantoinaseoxoprolinase, N-terminal
    1. PF05378 (Hydant_A_N)

Protein sequence

>MCA_00178_1
MSSQGKIRISIDRGGTFTDFFAHVPGPNSQDIVFKLLSVDPANYKDAPTEGIRRILEKVTGNQIPRGDPIDLEPVESIRM
GTTVATNALLERKGDRVAFIVTKGFGDILQIGQQARPSIFDLKVSKLKQIYEQVYEVDERITLEGYSENPEDDSFLDHKD
ENCVVGTSGELIRILKRPDTSKIQEMLDKIWQSGIRSLAITFMHSYIFPEHEKIVAGMARKMGFDCSVSSEIQPMIKLVS
RANSSTADAYLSPITTRYVQNFGKGFKGGLEAVGNKLLFMQSDGGLTSWSTFSGLKAILSGPAGGVVGYSKTSYDEDEKI
PILGFDMGGTSTDVSRYSGTLEHIFETTTAEVTIQSPQLDINTVAAGGGSILSWRKGLFAVGPESASAHPGPACYRKGGP
LTVTDANLFLGRIVPDFFPHIFGPAENEPLDTNIVKTKFHELTDVINKDRAGMKPLTAEEVAMGFLTVANEAMCRPIRTL
TEGKGYVASKHHLSSFGGAGGQHACSVANILGISKVVVHKYSSILSAYGMSLADVVFEVQRPESVTLSSASLAGLETRLE
EISQEAISNLVSQGFEAKNIKVEKYLNLRYNGTETFIMTMKEEDTAGFSFAEKFIQKHKLEFGFSLERDILVGDIRVRAI
GQTVLEEGTTPGADIKANGSNFVSVDKAKSIGATSIYFETHTGEGKWINDTPIYPLKNLSRGDQIKGPAIIIDDTQTILV
ELNAVATILTNHVIIDLDTSATSKQEDSSEALVIDPVQLSVFGHRFMSIAEQMGQTLQKTSISANIKERLDFSCAIFSPD
GGLVANAPHIPVHLGSMSTAVEYQKNMWEGKLNPGDVLVANHPAFGGSHLPDITVITPVFDADGKSIIFWAASRGHHSDI
GGITAGSMPPFSKELWEEGAMIKGFKVVENGVFKEDEMVDVLYTQPSKYPGCSGSRSLADSISDLKAQIAANNKGILLLN
DLIREFGLKTVQFYMYGIQKNAEMAVRELLKGISARFLAEHKDTGVKRDSQDRIILKARDQLDDGTPIELAIAINSETGE
ALFDFSNTGPQVYGNLNAPRAITQSAILYVLRSLISDNIPLNQGCLQPIEIYIPPGTILSPDADRATVGGNVETSQRITD
VILKAFESMGASQGTCNNLTFGYGGSTNTSSNNNKNKGKGFGYYETIAGGAGAGPSWDGQSGVQVHMTNTRSTDPEILEK
RYPCILHEFSLRRGSGGRGQFCGGDGVVRDIEFRVGVQVSILSERRARAPYGMRGGRDGQCGENLWLKLDNNDDGEEKDK
KFTTISLGGKNTVVMKPGDHVVIKTPGGGGYGDERLREVKKTDVIEGPAGFIPRASGSIAERTLLGESSA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0016787 hydrolase activity

Cellular Component

None predicted.