MCA_00141_1

Protein

Length

512 amino acids

Gene name: DUG1B

Description: Cys-Gly metallodipeptidase DUG1

Browser: contigA:379185-380804-

RNA-seq: read pairs 1323, FPKM 31.9, percentile rank 54.4% (100% = highest expression)

Protein function

Annotation:		DUG1B	Cys-Gly metallodipeptidase DUG1
KEGG:	K15428	DUG1	Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
EGGNOG:	0PHND	FG09893.1	glutamate carboxypeptidase
SGD closest match:	S000001940	DUG1	Cys-Gly metallodipeptidase DUG1
CGD closest match:	CAL0000193256	DUG1	Cys-Gly metallodipeptidase DUG1

Protein alignments

	%id	Aln length	E-value
MIA_05736_1	69.89%	435	0.0	MIA_05736_1
A0A0J9XFY9_GEOCN	61.99%	513	0.0	Similar to Saccharomyces cerevisiae YFR044C DUG1 Cys-Gly metallo-di-peptidase OS=Geotrichum candidum GN=BN980_GECA14s01275g PE=4 SV=1
A0A1E4TJT4_9ASCO	61.60%	474	0.0	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30276 PE=4 SV=1
A0A060T1K2_BLAAD	58.13%	504	0.0	ARAD1C25366p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25366g PE=4 SV=1
UniRef50_A0A0B4HK94	57.98%	476	0.0	Glutamate carboxypeptidase (Fragment) n=8 Tax=leotiomyceta TaxID=716546 RepID=A0A0B4HK94_9HYPO
A0A1E3PPE0_9ASCO	57.80%	481	0.0	Glutamate carboxypeptidase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49730 PE=4 SV=1
Q6C1A8_YARLI	59.29%	479	0.0	YALI0F17842p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F17842g PE=4 SV=1
DUG1_CANAL	57.05%	482	1e-179	Cys-Gly metallodipeptidase DUG1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DUG1 PE=1 SV=1
A0A161HGA0_9ASCO	61.01%	436	4e-179	Metallodipeptidase OS=Sugiyamaella lignohabitans GN=DUG1 PE=4 SV=1
DUG1_YEAST	55.00%	480	5e-171	Cys-Gly metallodipeptidase DUG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DUG1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9962
Predicted cleavage: 49

Protein family membership

Peptidase M20 (IPR002933)
- Cytosolic nonspecific dipeptidase/DUG1 (IPR017153)

Domains and repeats

Domain
247 - 404
Peptidase M20, dimerisation domain (IPR011650)

1 50 100 150 200 250 300 350 400 450 512

Detailed signature matches

IPR002933

Peptidase M20
1. PF01546 (Peptidase_M20)
  
  133 - 506
  
  Pfam
  PF01546 (Peptidase_M20)
IPR017153

Cytosolic nonspecific dipeptidase/DUG1
1. cd05676 (M20_dipept...)
  
  40 - 512
  
  CDD
  cd05676 (M20_dipept_like_CNDP)
2. PIRSF037242 (CNDP_d...)
  
  29 - 512
  
  PIRSF
  PIRSF037242 (CNDP_dipeptidase)
IPR011650

Peptidase M20, dimerisation domain
1. PF07687 (M20_dimer)
  
  247 - 404
  
  Pfam
  PF07687 (M20_dimer)
IPR001261

ArgE/DapE/ACY1/CPG2/YscS, conserved site
1. PS00759 (ARGE_DAPE_...)
  
  169 - 208
  
  PROSITE patterns
  PS00759 (ARGE_DAPE_CPG2_2)

no IPR

Unintegrated signatures

G3DSA:3.30.70...

254 - 423

GENE3D
G3DSA:3.30.70.360 (G3DSA:3.30.70.360)
G3DSA:3.40.63...

40 - 253

GENE3D
G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
SSF53187 (Zn-depend...)

38 - 250

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

424 - 508

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

active site cd05676

137H

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

171D

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

205E

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

206E

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

234D

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

236Y

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

249L

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

382R

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

419H

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

453E

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

455G

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

456S

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

457I

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

484H

active site
137H, 171D, 205E, 206E, 234D, 236Y, 249L, 382R, 419H, 453E, 455G, 456S, 457I, 484H
CDD
cd05676 (M20_dipept_like_CNDP)
metal binding site...

137H

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

171D

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

205E

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

206E

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

234D

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)

484H

metal binding site
137H, 171D, 205E, 206E, 234D, 484H
CDD
cd05676 (M20_dipept_like_CNDP)
dimer interface cd...

141Q

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

147D

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

250R

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

252V

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

254Y

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

256S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

262P

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

263N

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

264T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

265D

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

267H

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

268S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

269G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

270M

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

271F

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

272G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

273G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

274T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

275T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

276Y

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

277E

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

279M

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

283V

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

286M

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

287S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

290V

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

291T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

292P

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

326L

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

329A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

330L

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

331G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

334T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

335I

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

343A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

346A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

347R

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

352A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

353L

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

354S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

355I

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

356H

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

357G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

358V

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

359E

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

363S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

364S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

365P

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

366G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

367A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

368K

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

369T

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

370V

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

372P

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

373S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

378K

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

382R

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

407L

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

408N

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

410K

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

419H

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

454G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

455G

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

483A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

484H

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

485S

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

486A

dimer interface
141Q, 147D, 250R, 252V, 254Y, 256S, 262P, 263N, 264T, 265D, 267H, 268S, 269G, 270M, 271F, 272G, 273G, 274T, 275T, 276Y, 277E, 279M, 283V, 286M, 287S, 290V, 291T, 292P, 326L, 329A, 330L, 331G, 334T, 335I, 343A, 346A, 347R, 352A, 353L, 354S, 355I, 356H, 357G, 358V, 359E, 363S, 364S, 365P, 366G, 367A, 368K, 369T, 370V, 372P, 373S, 378K, 382R, 407L, 408N, 410K, 419H, 454G, 455G, 483A, 484H, 485S, 486A
CDD
cd05676 (M20_dipept_like_CNDP)

Protein sequence

>MCA_00141_1
MILSTSIRSINRSTLRVSAKSLLTRREFSYSVKKQNLNRVFSKIDELSPTFINRIRDAVAIPSVSSEPERRGELFKMAKF
LEHQAESLSFSLKPYDVGTQPQFKDESGNPLPLPPVLVGKYGNFEDKSKKTILIYGHYDVQPASLEDGWEMNPFILNEKE
DGKMIARGITDDKGPVIGWFNAIEAYQKAGVELPVNLVFCLEGMEESGSEGLDEFIKAQKDKEFKDIDAICISDNYWIGT
KHPVLTYGLRGVSYYSIEISGPNTDLHSGMFGGTTYEPMTDLVHVMSKLVTPNGKILIPGVNEMVAPLTKQESKLYDGIH
FELNDLKDALGNDTIIQDTPQGALMARWRFPALSIHGVEGAFSSPGAKTVIPSKVIGKFSIRTVPNIELDKLDECVFNYV
KKNFASLNSKNNLNVQLVHAGKWWVSDPNNWSFEAAVKATKDVWNVSPDMTREGGSIPVTLTFESQLEKPVLLLPMGRGD
DGAHSASEKLDKINYLQGTKTMAAYLYYASQT

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0008152 metabolic process

Molecular Function

GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features