Protein

MCA_00103_1

Length
315 amino acids

Gene name: PLC2

Description: phosphatidylinositol phospholipase C

Browser: contigA:278478-279426-

RNA-seq: read pairs 3556, FPKM 139.0, percentile rank 83.9% (100% = highest expression)

Protein function

Annotation:PLC2phosphatidylinositol phospholipase C
KEGG:K01771plc 1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]
EGGNOG:0PKC3FG00423.1phosphatidylinositol phospholipase C
CGD closest match:CAL0000198521PLC2Plc2p

Protein alignments

%idAln lengthE-value
MIA_04161_161.66%3132e-148MIA_04161_1
A0A060T285_BLAAD53.97%3154e-125ARAD1C26994p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26994g PE=4 SV=1
A0A0J9XDQ6_GEOCN55.41%3053e-124Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA11s00549g PE=4 SV=1
A0A161HJV2_9ASCO51.97%3042e-118Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1356 PE=4 SV=1
UniRef50_A0A161HJV251.97%3044e-115Uncharacterized protein n=2 Tax=Trichomonascaceae TaxID=410830 RepID=A0A161HJV2_9ASCO
Q5A0L4_CANAL50.16%3076e-106Plc2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PLC2 PE=4 SV=1
Q6C9J1_YARLI47.49%2991e-94YALI0D10813p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D10813g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1500

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 315

Detailed signature matches

  1. Domain IPR017946
    PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
    1. SSF51695 (PLC-like ...)
    2. G3DSA:3.20.20...
  2. Domain IPR000909
    Phosphatidylinositol-specific phospholipase C, X domain
    1. PS50007 (PIPLC_X_DO...)
    2. PF00388 (PI-PLC-X)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd08586 (PI-PLCc_Bc...)

Residue annotation

  1. catalytic site cd0...
  2. active site cd08586
  3. putative metal bin...

Protein sequence

>MCA_00103_1
MPPLATAGFSDLIEWQKNIGDNVLLSQLSIPGTHNSSACYVSLPSVQCQGASVAEQLVHGIRFFDFRVARPFTTKLGNAF
GKDNDDLQIIHGKFPVRIPFPVMLEDELNEIYSFLEKHPSECVMVSLKSEGSDKWGEFEFPNLIWEKYIKPHEDRWYLKN
KVPRMGEVRGKAFLFRRFGVPQERLVDYGFDAAWWKYNTPQDNRGRIDVQDFNEVNEPADVDKKITYINNHIERAVQYNS
TADATQEDTAKLFVNFCSGSNFFNKSCWPYEVSQGVRSKINYSNNAIGMGLIILDYAEVGDWEVPRKLIQLNYEG

GO term prediction

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0008081 phosphoric diester hydrolase activity

Cellular Component

None predicted.