Protein

MCA_00095_1

Length
523 amino acids

Gene name: PPT1

Description: serine/threonine-protein phosphatase

Browser: contigA:255333-256905+

RNA-seq: read pairs 768, FPKM 18.1, percentile rank 38.8% (100% = highest expression)

Protein function

Annotation:PPT1serine/threonine-protein phosphatase
KEGG:K04460PPP5C serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
EGGNOG:0PGEWFG07395.1serine threonine-protein phosphatase
SGD closest match:S000003355PPT1Serine/threonine-protein phosphatase T
CGD closest match:CAL0000195801PPT1Serine/threonine-protein phosphatase

Protein alignments

%idAln lengthE-value
MIA_04152_173.01%5150.0MIA_04152_1
A0A0J9X608_GEOCN61.99%5130.0Serine/threonine-protein phosphatase OS=Geotrichum candidum GN=BN980_GECA04s01000g PE=3 SV=1
A0A167E224_9ASCO59.84%5130.0Serine/threonine-protein phosphatase OS=Sugiyamaella lignohabitans GN=PPT1 PE=3 SV=1
UniRef50_G0S7H556.03%5140.0Serine/threonine-protein phosphatase n=84 Tax=Opisthokonta TaxID=33154 RepID=G0S7H5_CHATD
Q6CFH3_YARLI55.27%5120.0Serine/threonine-protein phosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B06963g PE=3 SV=1
A0A060SZJ0_BLAAD55.69%5100.0Serine/threonine-protein phosphatase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08360g PE=3 SV=1
A0A1D8PJ89_CANAL43.01%5722e-150Serine/threonine-protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PPT1 PE=3 SV=1
PPT1_YEAST44.32%5285e-148Serine/threonine-protein phosphatase T OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PPT1 PE=1 SV=1
A0A1E4TJI5_9ASCO37.22%3523e-60Serine/threonine-protein phosphatase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30199 PE=3 SV=1
A0A1E3PJ12_9ASCO41.70%2593e-61Serine/threonine-protein phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46742 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0104

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Repeat
  4. Repeat
1 50 100 150 200 250 300 350 400 450 523

Detailed signature matches

  1. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  2. Domain IPR013026
    Tetratricopeptide repeat-containing domain
    1. PS50293 (TPR_REGION)
  3. Domain IPR013235
    PPP domain
    1. PF08321 (PPP5)
  4. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  5. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  6. Domain IPR006186
    Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    1. PS00125 (SER_THR_PH...)
    2. SM00156 (pp2a_7)
    3. PR00114 (STPHPHTASE)
  7. Repeat IPR019734
    Tetratricopeptide repeat
    1. PS50005 (TPR)
    2. SM00028 (tpr_5)
    3. PF13181 (TPR_8)
  8. Repeat IPR001440
    Tetratricopeptide repeat 1
    1. PF00515 (TPR_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.15...
  2. G3DSA:1.20.58...
  3. PIRSF033096 (PPPtase_5)
  4. cd07417 (MPP_PP5_C)

Residue annotation

  1. metal binding site...
  2. active site cd07417
  3. TPR interaction si...

Protein sequence

>MCA_00095_1
MSSDNELKEKADQLKVKGNKALQQNHYDEAIKYYTEAIELYPKNEVYYANRAQAHIKNESYGSAIEDATKAIEINPAYMK
SYYRRGVALAAILRHAEALKDFKLVVNRVPSDVHAKNNLLSCQKIVRAKAFAKAIEIQDAPSTIESIDLKSLPLEDGYDG
LPLEITFNDKSSTPPPAKSAQDSNVLDESESKALAKIRSLLSKVEVNMTKEFIQDLIERFKTGKVVAKKYLYAIVMQAMK
HFIDEPSLVEIDLDKTPETFITVCGDTHGQYFDLINMFELNGYPDEHHMYLFNGDFVDRGSWSTEIAILFFAYKCLYPNS
FFLNRGNHEADGMNKMYGFEGECKAKYKSDNIFKIFSEAFCMLPLATLIHKSYLVLHGGLFSSDDVTLDDIKKIDRFAQK
QPGNSGLMMEILWTDPQVAPGRSASKRGVGIQFGPDVTAKFCEKNNLKAIIRSHEVRMGGYEKEHNGKLYTIFSAPNYCD
SQGNLGAYCNIKAPKYELDFKTFEAVPHPNIQPMAYANQMMRM

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.