Protein

MCA_00062_1

Length
965 amino acids

Gene name: DAP2

Description: Dipeptidyl aminopeptidase

Browser: contigA:153706-156604-

RNA-seq: read pairs 4632, FPKM 59.2, percentile rank 69.0% (100% = highest expression)

Protein function

Annotation:DAP2Dipeptidyl aminopeptidase
KEGG:K01282E3.4.14.- dipeptidyl aminopeptidase [EC:3.4.14.-]
EGGNOG:0PGX8DAPBType IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N- termini provided that the penultimate residue is proline (By similarity)
SGD closest match:S000001070DAP2Dipeptidyl aminopeptidase B
CGD closest match:CAL0000190899DAP2Dap2p

Protein alignments

%idAln lengthE-value
MIA_04121_170.34%7720.0MIA_04121_1
A0A0J9XA51_GEOCN57.52%8640.0Similar to Saccharomyces cerevisiae YHR028C DAP2 Dipeptidyl aminopeptidase, synthesized as a glycosylated OS=Geotrichum candidum GN=BN980_GECA05s05268g PE=4 SV=1
A0A060T419_BLAAD52.07%8220.0ARAD1C38214p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38214g PE=4 SV=1
UniRef50_A0A060T41952.07%8220.0ARAD1C38214p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T419_BLAAD
A0A167CK21_9ASCO52.74%7660.0Dap2p OS=Sugiyamaella lignohabitans GN=DAP2 PE=4 SV=1
A0A1E3PHU6_9ASCO52.32%7550.0Dipeptidyl aminopeptidase, synthesized as a glycosylated OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70480 PE=4 SV=1
Q6CFX2_YARLI43.37%8300.0YALI0B02838p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02838g PE=4 SV=1
A0A1E4THU8_9ASCO49.63%6750.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25993 PE=4 SV=1
DAP2_YEAST45.25%7580.0Dipeptidyl aminopeptidase B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAP2 PE=1 SV=2
A0A1D8PNK0_CANAL41.69%7580.0Dap2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DAP2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0022

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 965

Detailed signature matches

  1. Domain IPR002469
    Dipeptidylpeptidase IV, N-terminal domain
    1. PF00930 (DPPIV_N)
  2. Domain IPR029058
    Alpha/Beta hydrolase fold
    1. SSF53474 (alpha/bet...)
    2. G3DSA:3.40.50...
  3. Domain IPR001375
    Peptidase S9, prolyl oligopeptidase, catalytic domain
    1. PF00326 (Peptidase_S9)
  4. SITE IPR002471
    Peptidase S9, serine active site
    1. PS00708 (PRO_ENDOPE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:2.140.1...
  3. NON_CYTOPLASM... (N...)
  4. SSF82171 (DPP6 N-te...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. mobidb-lite (disord...)

Protein sequence

>MCA_00062_1
MPKDETVENHNQISQPSSSNNINTAPEPFNRSSIDSDSSTISSILEEINQHAAATQKAAKAKSKTSARNIPYSDINNTTS
SSFHANDYEMRQLNDNDFDTMDLEFSSDEEDNSALFHSHKKVHGQDNLIKNRRNRRILIILASVIATLLLGSLAVYLFST
PISTKSSASAAETDESISKPATSAAVVNTVYESSMPGLSPPKVDSSKQLFQMDDWRSGKLRPQLESLEWVAPAPGESKEQ
LLEDSEEGYALVDWPDRKSRKIIFDEEKRVFSYKKKLYMVHEIVLSPNKKYAILITNPEKNYRHSSFADYFIYDFEKNLY
LPLSPKESDDKIAIAKWSPLSDKIAYVLNNNLFIRNVNSTDVKQITKDGGADIFYGRPDWVYEEEVFASDTALWWSPKGD
YLAYLRTNDSQVEEFPIPYFVQKTPPSDHPYPILKKIKYPKPGSPNPIVDLLFLDLSTYESFSVPVEENEAEDTEKLITE
VVWTGDEKLIMRITDRDSSVLKVGVVDAKNKKGTTSRIVDVGKDGGWFEISQNTHFIPKDPEQGRPEDGYIDINVIDGYN
HLVYYSPIEAKEPKSVLTSGKWEVDDSEVAYNAKTNRVYFTSTKKSPVERHVYSVKLDGTDLKALTNESNEGWYKASYSP
SSRYVLLNNMGPSVPSQVVLDLESDDVWGPDSAIPLGNNDQLKKTLKEYEMPTEIYSQIKVGTDKNGTDIMANAVEYRPP
NFNETLKYPVLFYVYGGPVSQMVQKTFSYSFQQVVASSINAIVVTVDGRGTGFMGRDFRSVIRGRLGDYEVQDQIAAAKE
WKSRSYVDSDRIAIWGWSYGGFMTLKTLETDAGNNFKYGMAVAPVTDWRFYDSIYTERYMHVPEKNKEGYGFSEITDVGN
MSQSTRFLVMHGTGDDNVHFQHTLTLLDKLDLAKVENYDVHVFPDSDHSIYYHGANTIVYDKLLHWISNAFAGKYNGFMK
KRSQI

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity

Cellular Component

None predicted.