Protein

MCA_00059_1

Length
977 amino acids

Gene name: RPN1

Description: 26S proteasome regulatory subunit RPN1

Browser: contigA:147939-150873-

RNA-seq: read pairs 10588, FPKM 133.8, percentile rank 83.4% (100% = highest expression)

Protein function

Annotation:RPN126S proteasome regulatory subunit RPN1
KEGG:K03028PSMD2 26S proteasome regulatory subunit N1
EGGNOG:0PFH6RPN126S proteasome regulatory subunit
SGD closest match:S000001069RPN126S proteasome regulatory subunit RPN1
CGD closest match:CAL0000177742RPN1Proteasome regulatory particle base subunit

Protein alignments

%idAln lengthE-value
MIA_04119_176.49%9230.0MIA_04119_1
A0A0J9X8B9_GEOCN70.00%9200.0Similar to Saccharomyces cerevisiae YHR027C RPN1 Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome OS=Geotrichum candidum GN=BN980_GECA05s05180g PE=4 SV=1
A0A060T8M6_BLAAD67.17%9350.0ARAD1C38148p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38148g PE=4 SV=1
A0A167CJZ0_9ASCO66.44%8940.0Proteasome regulatory particle base subunit RPN1 OS=Sugiyamaella lignohabitans GN=RPN1 PE=4 SV=1
UniRef50_A0A167CJZ066.44%8940.0Proteasome regulatory particle base subunit RPN1 n=42 Tax=Dikarya TaxID=451864 RepID=A0A167CJZ0_9ASCO
A0A1E3PHJ5_9ASCO62.82%9360.026S proteasome regulatory subunit rpn-1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46714 PE=4 SV=1
A0A1E4TGH4_9ASCO53.33%9450.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_68858 PE=4 SV=1
Q6CFX0_YARLI56.54%6190.0YALI0B02860p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02860g PE=4 SV=1
A0A1D8PFL7_CANAL56.52%5980.0Proteasome regulatory particle base subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPN1 PE=4 SV=1
RPN1_YEAST50.74%6079e-17826S proteasome regulatory subunit RPN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0236

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 100 200 300 400 500 600 700 800 900 977

Detailed signature matches

  1. Family IPR016643
    26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit
    1. PIRSF015965 (26S_pr...)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  4. Repeat IPR002015
    Proteasome/cyclosome repeat
    1. PF01851 (PC_rep)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00059_1
MTDSEKSAKSTNQSSDSKSQSASSSSSKDNNKNKKNQKQQQQEEELSEEDEKLKNELEMLVERLKEKNTELYVPALNSLK
TFIRTSTSSMTAVPKPLKFLRPHYPALTKVYETWSETLKPILADVLSVLAMTYAGDGNRDSLKYRLLATPTSSTSSSSQT
EASTTTEGSEKEDDISSWGHEYMRHLALEIGEEYALRTENEEATDDLLSLSLKIVPYFLKHNAEADAVDLLMEVESIEAL
PEYVDTNNFARVCLYMVSCVPLLPPPDDLAFLHTAYQIYLTHGQLTQALALAIRIDDIDLIDSCFQATTDTLVQKQLAFI
LARQQYFYQVEDEDVNKCLSNLHLSEDFLYLTKELNLTDPKVPEDVYKSHLENAMLGSTLLASAKQNLASAFVNAFLNYG
YCNDKLLTVESESDSFIYQTKDSGLASTTASLGLLYHWNHTEGLQNLDRYLYSNDKHIKAGAILGVGVVNAGVQDDTDPA
LALLEEYITNPDETVLNKTSAILGLGLSYAGSRKDSLTELLSPLILDTSQSMHVSSIAALALGHIFVGSADGEIATIILG
TLLERTQEQLSDKWTRFMALGLGLLFLGKYQLTEEVMETIKAIDHPISSVVDVLVTICSYAGTGNVLQIQKLLHNCTTKV
EVDEDEEEDEQEEAQAGSLGTAPGAAEPESSTAAETSTPVKSSTEEPKASGAPSKTENTESDEASVEKAFFDSQVQGFSV
LGLATIAMGEDIGQEMVLRHFSHLMHYGEAHIRRSVPLAMGLVSASNPEMKVFDTLSRYSHDSDLDVAINAIFSMGVVGA
GTNNARLAQLLRQLASYYVREPDSLFTVRIAQGLLHMGKGTLTLNPFNTERQILSRVSLAGLLTVAVAWMDPQSFILSSS
HSILYFLTSAIRPRMLVTVDENLEPIKVNVRVGQAVDVVGQAGKPKTITGWVTHSTPVLLGYGERAELEDDEYTSLSHVL
EGIVILKKNDDRMDVDN

GO term prediction

Biological Process

GO:0042176 regulation of protein catabolic process

Molecular Function

GO:0005488 binding
GO:0030234 enzyme regulator activity

Cellular Component

GO:0000502 proteasome complex