Protein

MCA_00044_1

Length
341 amino acids

Gene name: CAB4

Description: phosphopantetheine adenylyltransferase, subunit of the CoA-synthesizing protein complex

Browser: contigA:107111-108355+

RNA-seq: read pairs 2363, FPKM 85.4, percentile rank 76.3% (100% = highest expression)

Protein function

Annotation:CAB4phosphopantetheine adenylyltransferase, subunit of the CoA-synthesizing protein complex
KEGG:K02201E2.7.7.3B pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
EGGNOG:0PMC5Pantetheine-phosphate adenylyltransferase
SGD closest match:S000003509CAB4Phosphopantetheine adenylyltransferase
CGD closest match:CAL0000187822orf19.1776Putative pantetheine-phosphate adenylyltransferase

Protein alignments

%idAln lengthE-value
MIA_04048_156.20%3632e-144MIA_04048_1
A0A0J9XCF4_GEOCN58.06%3414e-138Similar to Saccharomyces cerevisiae YGR277C CAB4 Probable pantetheine-phosphate adenylyltransferase (PPAT),which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate OS=Geotrichum candidum GN=BN980_GECA09s01121g PE=4 SV=1
UniRef50_A0A0J9XCF458.06%3417e-135Similar to Saccharomyces cerevisiae YGR277C CAB4 Probable pantetheine-phosphate adenylyltransferase (PPAT),which catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCF4_GEOCN
A0A060TBI7_BLAAD44.28%3321e-90ARAD1B08118p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08118g PE=4 SV=1
A0A167CLV4_9ASCO41.98%3432e-81Putative pantetheine-phosphate adenylyltransferase OS=Sugiyamaella lignohabitans GN=CAB4 PE=4 SV=1
Q6C8I1_YARLI38.27%3711e-80YALI0D19426p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D19426g PE=4 SV=2
A0A1E3PRU6_9ASCO36.07%3411e-73Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48790 PE=4 SV=1
A0A1E4TE90_9ASCO47.71%1533e-48Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12669 PE=4 SV=1
COAD_YEAST46.31%1491e-40Phosphopantetheine adenylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CAB4 PE=1 SV=1
A0A1D8PII4_CANAL41.24%1775e-37Putative pantetheine-phosphate adenylyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1776 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1768

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 341

Detailed signature matches

  1. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
  2. Domain IPR004821
    Cytidyltransferase-like domain
    1. PF01467 (CTP_transf...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)

Protein sequence

>MCA_00044_1
MFFASTLVLVAATDYHRIQHLYSEVISHALYNTMNNGSLDIMVMKSSGSLFAIERITAGFYAIAHKENESLRRRNITITV
LLDGRNIELSRKQSWEVIVAGKYEDDLLQEFHNLVPANSKLLALPTLIVHMTDPASKFDAIQEDPKEASDPTNGLVFKDS
SDEQLFYDSKGDEVAAGEWEHDVVAVGGTFDHLHDGHRLLLTIGGYLAKEKLIVGITGSELLVNKKYAEVMQSYMIRRQA
VEEFLSYVFPQLEVETYMLHDVAGPAGAIEGIDALVLSRETVQGGQEVNRIRKAKNFKPLIIYQVDVIGCITGNATNNYH
DKLSSTELRRLEFEKLKISDN

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.