Protein

MCA_00041_1

Length
462 amino acids

Browser: contigA:100629-102018+

RNA-seq: read pairs 1812, FPKM 48.4, percentile rank 64.7% (100% = highest expression)

Protein function

EGGNOG:0PM13Guanine deaminase
SGD closest match:S000002397GUD1Probable guanine deaminase
CGD closest match:CAL0000177418orf19.7029Guanine deaminase

Protein alignments

%idAln lengthE-value
A0A0J9XEI5_GEOCN83.33%4620.0Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA13s00461g PE=4 SV=1
MIA_04044_182.03%4620.0MIA_04044_1
UniRef50_Q9234270.69%4640.0Uncharacterized protein C1F8.04c n=82 Tax=cellular organisms TaxID=131567 RepID=YDI4_SCHPO
A0A1D8PQQ8_CANAL27.13%3762e-22Guanine deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7029 PE=4 SV=1
S6EAV4_BLAAD24.11%4481e-22Guanine deaminase (Fragment) OS=Blastobotrys adeninivorans GN=AGDA PE=4 SV=1
GUAD_YEAST24.32%3702e-22Probable guanine deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUD1 PE=1 SV=1
Q6C4L7_YARLI23.50%3836e-22YALI0E25740p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25740g PE=4 SV=1
A0A1E3PT60_9ASCO26.67%2702e-21Metallo-dependent hydrolase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45114 PE=4 SV=1
A0A170QZU5_9ASCO28.81%1772e-18Guanine deaminase OS=Sugiyamaella lignohabitans GN=GUD1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0523

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 462

Detailed signature matches

  1. Domain IPR011059
    Metal-dependent hydrolase, composite domain
    1. SSF51338 (Composite...)
    2. G3DSA:2.30.40.10
  2. Domain IPR032466
    Metal-dependent hydrolase
    1. SSF51556 (Metallo-d...)
  3. Domain IPR006680
    Amidohydrolase-related
    1. PF01979 (Amidohydro_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.20.20...
  2. cd01298 (ATZ_TRZ_like)

Residue annotation

  1. active site cd01298
  2. putative substrate...

Protein sequence

>MCA_00041_1
MLYTHATIITVNKDREIIEDGAIYVKEGSSTIDDIGKTETLKEKYPEEPTTDFTGHIVMPGLISLHVHLAQSLLRSAADD
LELISWLCDRVWPMQGHFTEEDGYVASQLTIAEMLKSGTTCFVEALFAERYGFEGAVRAVVESGIRGCIGKVVMDQPRYA
TQSGISMEPGLIEDETSLDNALKCYEKFDGAGNGRVEVWFGARTPGGVTEGLYRKMSKIAREKNIGITMHCAEIKADSEF
FASKGHTPMTYCKENGLLGPRTVLAHMVHLDDNDIKILSETEASIAHCPTSNAKLGSGIARVKEYLEANLTVGIGCDGCP
CNNVMDMLQEMKLASLLPKAIHYTPDIVPAETIIEMATIQGAKAIGHEKTLGSLEIGKKADFISINLSDKIYGVPHRDPC
SAVVYIATGNDVENVIVDGKQLIKNGELLTMDIKDIIKKAQVHGEAVRERANIPLGGRWKKV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.