Protein

MCA_00006_1

Length
719 amino acids


Description: protein with copper fist DNA-binding domain

Browser: contigA:18491-20727+

RNA-seq: read pairs 991, FPKM 17.0, percentile rank 37.0% (100% = highest expression)

Protein function

Annotation:protein with copper fist DNA-binding domain
EGGNOG:0PGCCPGUG_00224copper ion binding
SGD closest match:S000004623MAC1Metal-binding activator 1
CGD closest match:CAL0000188166MAC1Metal-binding activator 1

Protein alignments

%idAln lengthE-value
MIA_04075_144.59%2225e-41MIA_04075_1
A0A0J9XAI3_GEOCN69.23%521e-17Similar to Saccharomyces cerevisiae YMR021C MAC1 Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport OS=Geotrichum candidum GN=BN980_GECA07s00516g PE=4 SV=1
UniRef50_A0A0J9XAI369.23%523e-14Similar to Saccharomyces cerevisiae YMR021C MAC1 Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAI3_GEOCN
A0A1E4THR5_9ASCO53.73%679e-16Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44889 PE=4 SV=1
MAC1_YEAST67.35%491e-14Metal-binding activator 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAC1 PE=1 SV=2
Q6C3W4_YARLI58.00%503e-13YALI0E31669p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E31669g PE=4 SV=1
A0A060T0A8_BLAAD55.36%562e-13ARAD1C15048p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C15048g PE=4 SV=1
MAC1_CANAL41.25%801e-10Metal-binding activator 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MAC1 PE=2 SV=1
A0A161HKY0_9ASCO48.78%412e-07Haa1p OS=Sugiyamaella lignohabitans GN=HAA1 PE=4 SV=1
A0A1E3PM57_9ASCO57.89%383e-07Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_77704 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0117

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 719

Detailed signature matches

    1. SM00412 (copper1)
    2. PF00649 (Copper-fist)
    3. SM01090 (Copper_fist_2)
    4. PR00617 (COPPERFIST)
    5. SSF57879 (Zinc doma...)
    6. PS50073 (COPPER_FIST_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00006_1
MIIYKDEKYSCLPCIRGHRSSTCNHSHRTLIRVRNRGRPSASEKRVAILPKEGNNVIVLKSRPTGTPLTDTEPSKISKKK
TTCGCCKGSQIQRINAESEATTNTNVASCKSSKCACSTQVRKTKNNELITIEGAIDQKFVEVGKSGTRFLSDEELKQSEM
NKKFYFISENPETGERKPISDDQRATDPTSLPNLESKDYIKLFCCCGSSDCDCANCEGCKYNLLLAKNIISRNRPVNEVF
STNSTNIQGEVKPDINENQNVGTLLPNSESIDPETTGLLNANHQSFIDLWSYQNPNSGNPISQQYKRGNGIFEILQNIDA
TGLSSAHDSSGNINTDIYHSNCDENSFKSHPKASSSNQRSSNKSCCGKRKGNCSSQSSNNAYPNNPPNITDTGKTIDTPS
TQFSGKGNNDFDALLNRQNQSGVYTSSIEKNSNDLSNHFKCEKKEINVENLSSCCKINYNDIFNTSFGSSDGHNLNTNDG
PSCFKLKNGLQKLALNDKSGKNTNDNVCDKNFNMTGDNNLNLFTSHDSATSENGNKTTQFNDLPIFPTYSSHVNEQQGQF
QGKSDIMNELAFKYDDPKAPDFILPMNNITEEIEKSLNKELTELFNACEDNNSPMLSSNSALMSFAPSCVLPGECQCGDG
CVCEGCVTHQKRSASFINDNIITNSENFAEGANQFDIDFFGDNIRRESQLMFDLKDMKTATNGQKKSDDIFQTRPSSNL

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005507 copper ion binding

Cellular Component

GO:0005634 nucleus