Protein

MCA_00002_1

Length
690 amino acids

Gene name: FAA4

Description: Long-chain-fatty-acid--CoA ligase 4

Browser: contigA:8286-10359+

RNA-seq: read pairs 4444, FPKM 79.5, percentile rank 75.1% (100% = highest expression)

Protein function

Annotation:FAA4Long-chain-fatty-acid--CoA ligase 4
KEGG:K01897ACSL long-chain acyl-CoA synthetase [EC:6.2.1.3]
EGGNOG:0PF89FAA4long-chain-fatty-acid--CoA ligase
SGD closest match:S000004860FAA4Long-chain-fatty-acid--CoA ligase 4
CGD closest match:CAL0000190605FAA4Long-chain fatty acid-CoA ligase

Protein alignments

%idAln lengthE-value
MIA_04088_177.00%6870.0MIA_04088_1
A0A0J9X586_GEOCN69.00%6870.0Similar to Saccharomyces cerevisiae YMR246W FAA4 Long chain fatty acyl-CoA synthetase OS=Geotrichum candidum GN=BN980_GECA02s09052g PE=4 SV=1
A0A060T221_BLAAD59.25%6700.0ARAD1A03982p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03982g PE=4 SV=1
A0A167DXV9_9ASCO60.00%6700.0Long-chain fatty acid-CoA ligase FAA4 OS=Sugiyamaella lignohabitans GN=FAA4 PE=4 SV=1
UniRef50_A0A167DXV960.00%6700.0Long-chain fatty acid-CoA ligase FAA4 n=7 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DXV9_9ASCO
A0A1E3PET7_9ASCO55.13%6820.0Acetyl-CoA synthetase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53378 PE=4 SV=1
Q6C8Q3_YARLI53.41%6890.0YALI0D17864p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17864g PE=4 SV=1
A0A1D8PU56_CANAL49.71%6920.0Long-chain fatty acid-CoA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FAA4 PE=4 SV=1
LCF4_YEAST49.14%6960.0Long-chain-fatty-acid--CoA ligase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FAA4 PE=1 SV=1
A0A1E4T9T3_9ASCO45.76%6950.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_124301 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0645

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 690

Detailed signature matches

  1. Domain IPR000873
    AMP-dependent synthetase/ligase
    1. PF00501 (AMP-binding)
  2. SITE IPR020845
    AMP-binding, conserved site
    1. PS00455 (AMP_BINDING)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.30.38.10
  3. G3DSA:3.30.30...
  4. G3DSA:3.40.50...
  5. SSF56801 (Acetyl-Co...)

Protein sequence

>MCA_00002_1
MAIKIKVNNKENVSAVVGPAQPGETAPRRNVGAKNAPWIYPDNNPEMNTIWNLLEWSVKEYTDLQAMGWRKIVDVHTEEK
MVTKKVDGKTVQIPKQWQYFELSGYTYITYRQLLQTVKEYAAGLMAIGIKPKGEETFHIYAQTSATWFQTALALNANAVP
VATAYDTLGEEGLTHTLVQTDSVGVLCDNNILHTLVEPLKSAKNIRIIITVDPIEQQSEKDAVEKILAINPNVKFYSYSE
LVALGKEKFVEPIKPSPEDVALIMYTSGSTGTPKGVVLTNANVAAGLAGVSGNITHEVIPPGSRLLAYLPLAHILEFTFE
LAVLFWGGVLGYGTVKTISDVSVRKCAGDIREFKPNVMVGVPAVWESVRKGVMSKVSQLSPIAQKVFWAAYRTKLRLLNR
NLPCPLVDNLIFKKIKEATGGQLKIVLNGGAAVSRVTQEFITTLIAPMVMGYGLTETNANCCLMTPKSFSFETQGELTHA
VTVKLVDVESDGYFAKNNQGEVLIKSGSLAKEYYKNEQETKEAFTDDGYFRTGDIGEWTENGHLKLIDRKKNLIKTLNGE
YIALEKLESFYRSNQYVLNICVYADETRVKPIAIVVPNAAAVEKLAAQLNIDHHEDIAHDPKVKAAIQKSMIQTGKDAGL
KGIELILGVVISNVEWSAQNGFLTSAQKLQRKKIVADNKKAIDELYDSAQ

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.